acute lung injury

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	411
interventional	249
Observational	148
Registry	14

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Drug	53
Other	41
Drug|placebo	36
Procedure	33
Device	31
Biological	11
Device|Other	9
Drug|Other	5
Behavioral	4
Biological|Other	4
Biological|placebo	4
Device|Procedure	3
Drug|Procedure	3
Behavioral|Other	2
Other|Procedure	2
Behavioral|Radiation	1
Biological|Drug	1
Biological|Procedure	1
Device|Drug	1
Diagnostic Test	1
Dietary Supplement|placebo	1
Drug|Other|Procedure	1
Drug|Radiation	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	74
France	40
China	19
NA	13
Italy	12
United Kingdom	10
Spain	9
United States|Canada	7
Canada	5
Germany	5
Austria	4
Brazil	4
Taiwan	4
Egypt	3
Korea, Republic of	3
Mexico	3
Netherlands	3
Turkey	3
Greece	2
Iran, Islamic Republic of	2
Japan	2
Russian Federation	2
Sweden	2
Thailand	2
Argentina	1
Austria|France|United Kingdom	1
Belgium	1
Canada|France	1
Canada|Saudi Arabia	1
Denmark	1
France|Italy|Spain|Tunisia	1
Norway	1
Singapore	1
Switzerland	1
United States|Australia|Belgium|Canada|New Zealand|Spain	1
United States|Australia|Canada|Malaysia|Netherlands|Thailand	1
United States|Austria|Germany|Israel	1
United States|France|Spain|United Kingdom	1
United States|Israel	1
United States|United Kingdom	1

Sites per Study

Site_count	Study_Count
1	169
2	20
3	4
4	7
5	12
6	5
7	3
8	1
9	1
10	2
12	1
13	1
14	4
15	1
16	2
17	2
19	1
20	1
21	2
24	1
29	3
39	1
43	1
44	1
47	2
110	1

Phase

Phase	Study_Count
N/A	120
Phase 2	44
Phase 3	32
Phase 1/Phase 2	17
Phase 1	15
Phase 4	14
Phase 2/Phase 3	5
Early Phase 1	2

Number of Arms

Number_of_Arms	Count_of_Studies
1	43
2	156
3	23
4	4
5	2
7	1
NA	20

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	9.0	5.0000	3.00000	9.0000	10.0000	43	11.0000	10.0000
1st Qu.	10.5	30.0000	14.50000	26.0000	39.5000	60	122.0000	50.0000
Median	12.0	75.0000	20.00000	40.0000	69.5000	313	259.0000	85.0000
Mean	12.0	161.2017	39.53333	102.7647	110.3864	328	417.3448	174.2143
3rd Qu.	13.5	184.0000	50.50000	86.0000	135.0000	524	500.0000	188.2500
Max.	15.0	1250.0000	190.00000	600.0000	580.0000	700	1500.0000	651.0000

Trial Group Type

group_type	Group_Count
Experimental	241
Active Comparator	100
Placebo Comparator	55
No Intervention	30
Other	26
NA	20
Sham Comparator	5

Intervention Model

intervention_model	Study_Count
Parallel Assignment	166
Single Group Assignment	53
Crossover Assignment	13
Factorial Assignment	7
Sequential Assignment	5
NA	5

Primary Purpose

primary_purpose	Study_Count
Treatment	186
Prevention	25
Diagnostic	15
Supportive Care	9
Other	7
Basic Science	3
Health Services Research	2
Screening	1
NA	1

Observational Studies

Studies by Country

Country	Study_Count
France	31
United States	27
China	14
Italy	11
NA	8
Taiwan	7
Spain	6
United Kingdom	6
Germany	4
India	3
Argentina	2
Belgium	2
Canada	2
Norway	2
Singapore	2
Sweden	2
Australia	1
Bangladesh|India|Iran, Islamic Republic of|Malaysia|Maldives|Nepal|Pakistan|Sri Lanka|Thailand|Vietnam	1
Belgium|France	1
Brazil	1
Brazil|Canada|Italy|Spain	1
Canada|China|France	1
Croatia	1
Cyprus|Finland|Netherlands	1
Egypt	1
Finland|France|Germany|Italy|Sweden|United Kingdom	1
France|Germany|Spain	1
Greece	1
Korea, Republic of	1
Lebanon	1
Malaysia	1
Sierra Leone	1
Turkey	1
United States|Austria|Belgium|Canada|France|Germany|Italy|Netherlands|Spain|Sweden|Switzerland|United Kingdom	1
United States|Estonia|Germany|Italy|Lithuania|Netherlands|Norway|Slovenia	1

Sites per Study

Site_count	Study_Count
1	119
2	6
3	2
4	4
5	3
6	2
7	1
11	1
13	1
15	1
16	1
18	1
19	1
20	1
26	1
28	1
51	1
58	1

Enrollment Metrics

Measure	Observational
Min	2.0000
1st Qu	35.0000
Median	100.0000
Mean	598.4236
3rd Qu	300.0000
Max	14000.0000

Observation Model

observational_model	Study_Count
Cohort	96
Case-Only	15
Case-Control	12
NA	9
Case Control	7
Other	7
Defined Population, Natural History	1
Natural History	1

Time Perspective

time_perspective	Study_Count
Prospective	119
Retrospective	14
Cross-Sectional	7
Other	3
NA	3
Cross-Sectional, Retrospective/Prospective	1
Longitudinal, Retrospective	1

Registries

Studies by Country

Country	Study_Count
Argentina	2
China	2
France	2
Spain	2
Belgium	1
Canada	1
Chile	1
China|Hong Kong|India|Indonesia|Japan|Malaysia|Pakistan|Singapore|Thailand|Vietnam	1
Denmark	1
Thailand	1

Sites per Study

Site_count	Study_Count
1	10
2	1
4	1
19	1
31	1

Enrollment Metrics

Measure	Registries
Min	29.000
1st Qu	49.000
Median	225.000
Mean	1521.643
3rd Qu	950.000
Max	11000.000

Registry Model

observational_model	Study_Count
Cohort	13
Case Control	1

Time Perspective

time_perspective	Study_Count
Prospective	13
Other	1

Follow-up

target_duration	Study_Count
60 Days	3
1 Year	2
28 Days	2
6 Months	2
1 Day	1
1 Month	1
2 Years	1
4 Days	1
90 Days	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03376854	Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS	https://ClinicalTrials.gov/show/NCT03376854	Recruiting	University of Maryland, Baltimore	2020-11-30
NCT04371016	Pulmonary and Ventilatory Effects of Bed Verticalization in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04371016	Recruiting	University Hospital, Clermont-Ferrand	2021-09-30
NCT04305457	Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19	https://ClinicalTrials.gov/show/NCT04305457	Active, not recruiting	Massachusetts General Hospital	2021-04-01
NCT04235608	SEvoflurane for Sedation in ARds	https://ClinicalTrials.gov/show/NCT04235608	Recruiting	University Hospital, Clermont-Ferrand	2024-05-03
NCT04023305	Sevoflurane PharmacokInetics in ARDS	https://ClinicalTrials.gov/show/NCT04023305	Recruiting	University Hospital, Clermont-Ferrand	2022-03-01
NCT03372525	Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03372525	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2020-12-31
NCT03371498	Procollagen-3 Driven Corticosteroids for Persistent Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03371498	Recruiting	Assistance Publique Hopitaux De Marseille	2020-06-15
NCT04397510	Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury	https://ClinicalTrials.gov/show/NCT04397510	Enrolling by invitation	Frederick Health	2020-12-31
NCT04308668	Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2	https://ClinicalTrials.gov/show/NCT04308668	Completed	University of Minnesota	2020-05-20
NCT03368092	Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma	https://ClinicalTrials.gov/show/NCT03368092	Recruiting	University Hospital, Strasbourg, France	2021-10-01
NCT03589482	Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure	https://ClinicalTrials.gov/show/NCT03589482	Recruiting	University Health Network, Toronto	2019-12-31
NCT03337373	The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium	https://ClinicalTrials.gov/show/NCT03337373	Completed	Mahidol University	2018-08-31
NCT03328117	A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury	https://ClinicalTrials.gov/show/NCT03328117	Completed	Exvastat Ltd.	2018-03-05
NCT03303807	Correction by ECCO2-R of Hypercapnia in Patients With DVP in Moderate to Severe ARDS Under Protective Ventilation.	https://ClinicalTrials.gov/show/NCT03303807	Completed	Assistance Publique - Hôpitaux de Paris	2019-02-25
NCT03296059	Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates	https://ClinicalTrials.gov/show/NCT03296059	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2021-10-01
NCT03281473	Comparison of Positive End Expiratory Pressure Titration Methods in ARDS Patients	https://ClinicalTrials.gov/show/NCT03281473	Recruiting	University Hospital, Angers	2019-12-31
NCT03217162	Surfactant for Neonate With Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03217162	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2021-07-30
NCT03217149	Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03217149	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2020-08-30
NCT03202641	Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients	https://ClinicalTrials.gov/show/NCT03202641	Recruiting	Massachusetts General Hospital	2020-04-01
NCT03202394	Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS	https://ClinicalTrials.gov/show/NCT03202394	Completed	BioMarck Pharmaceuticals, Ltd.	2020-03-30
NCT03111212	Iloprost in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03111212	Recruiting	University Hospital Tuebingen	2021-10-31
NCT03096314	Vitamin D to Improve Outcomes by Leveraging Early Treatment	https://ClinicalTrials.gov/show/NCT03096314	Completed	Massachusetts General Hospital	2018-12-11
NCT03089957	Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03089957	Recruiting	Peking University Third Hospital	2019-12-31
NCT03085615	Feeding the Critically Ill During Phases of Altered Redox Status	https://ClinicalTrials.gov/show/NCT03085615	Completed	University of Illinois at Chicago	2018-06-04
NCT03042143	Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (COVID-19)	https://ClinicalTrials.gov/show/NCT03042143	Recruiting	Belfast Health and Social Care Trust	2020-09-30
NCT03031275	Long-term Follow Up of Adult Patients Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure	https://ClinicalTrials.gov/show/NCT03031275	Completed	Karolinska University Hospital	2016-12-31
NCT03023670	Lung Protection and Pediatric Cardiac Surgery	https://ClinicalTrials.gov/show/NCT03023670	Completed	Assiut University	2018-03-31
NCT02978885	Imaging of Peri-operative (periOP) Lung Injury	https://ClinicalTrials.gov/show/NCT02978885	Recruiting	Columbia University	2020-09-30
NCT02963558	A Study Promoting Critical Illness Recovery in the Elderly	https://ClinicalTrials.gov/show/NCT02963558	Active, not recruiting	Wake Forest University Health Sciences	2021-06-30
NCT02895373	PGE1 as Additive Anticoagulant in ECMO-Therapy	https://ClinicalTrials.gov/show/NCT02895373	Recruiting	Medical University of Vienna	2019-07-31
NCT02892799	Non-invasive Fluid Management	https://ClinicalTrials.gov/show/NCT02892799	Recruiting	Intermountain Health Care, Inc.	2020-12-31
NCT02891837	L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects	https://ClinicalTrials.gov/show/NCT02891837	Completed	Asklepion Pharmaceuticals, LLC	2019-06-30
NCT02859194	The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients	https://ClinicalTrials.gov/show/NCT02859194	Completed	Yonsei University	2016-10-14
NCT02819453	Corticosteroid Mediates Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02819453	Completed	Shanghai Pulmonary Hospital, Shanghai, China	2017-07-31
NCT02816372	Ultra Protective Ventilation Without Extracorporeal Circulation in Severe ARDS Patients (VT4ARDS)	https://ClinicalTrials.gov/show/NCT02816372	Completed	Hospices Civils de Lyon	2018-06-14
NCT02816359	Position and Esophageal Pressure	https://ClinicalTrials.gov/show/NCT02816359	Completed	Hospices Civils de Lyon	2017-09-30
NCT02814994	Respiratory System Compliance Guided VT in Moderate to Severe ARDS Patients	https://ClinicalTrials.gov/show/NCT02814994	Completed	Southeast University, China	2014-05-31
NCT02804945	Mesenchymal Stem Cells (MSCs) for Treatment of Acute Respiratory Distress Syndrome (ARD) in Patients With Malignancies	https://ClinicalTrials.gov/show/NCT02804945	Completed	M.D. Anderson Cancer Center	2019-06-13
NCT02787720	Rehabilitation Techniques on Survivors of Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02787720	Completed	Baqiyatallah Medical Sciences University	2014-10-31
NCT02734654	Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage	https://ClinicalTrials.gov/show/NCT02734654	Completed	Instituto de Salud Carlos III	2011-02-28
NCT02713451	Liberal Oxygenation Versus Conservative Oxygenation in ARDS	https://ClinicalTrials.gov/show/NCT02713451	Active, not recruiting	Centre Hospitalier Universitaire de Besancon	2019-05-31
NCT02611609	A Phase 1/2 Study to Assess MultiStem® Therapy in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02611609	Completed	Athersys, Inc	2018-09-30
NCT02574169	Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation	https://ClinicalTrials.gov/show/NCT02574169	Recruiting	University Hospital, Toulouse	2019-03-31
NCT04370834	Tocilizumab for Patients With Cancer and COVID-19 Disease	https://ClinicalTrials.gov/show/NCT04370834	Recruiting	National Cancer Institute (NCI)	2021-11-01
NCT04327401	COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III	https://ClinicalTrials.gov/show/NCT04327401	Active, not recruiting	Hospital Sirio-Libanes	2020-08-30
NCT02546947	Monitoring in Intensive Care Unit of Neuromuscular Blocking Agents Used for Acute Respiratory Distress Syndrome After Cardiothoracic Surgery	https://ClinicalTrials.gov/show/NCT02546947	Completed	Centre Chirurgical Marie Lannelongue	2016-12-31
NCT02509078	Reevaluation Of Systemic Early Neuromuscular Blockade	https://ClinicalTrials.gov/show/NCT02509078	Completed	Massachusetts General Hospital	2018-07-03
NCT02468908	Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects	https://ClinicalTrials.gov/show/NCT02468908	Completed	Savara Inc.	2015-10-31
NCT02463773	Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS	https://ClinicalTrials.gov/show/NCT02463773	Completed	University of Minnesota	2016-07-31
NCT02450825	Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration	https://ClinicalTrials.gov/show/NCT02450825	Completed	Centre hospitalier de l’Université de Montréal (CHUM)	2017-02-28
NCT02425579	Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT02425579	Completed	Brigham and Women’s Hospital	2019-08-31
NCT02416037	Trans-pulmonary Pressure in ARDS	https://ClinicalTrials.gov/show/NCT02416037	Completed	Hospices Civils de Lyon	2017-04-13
NCT02403791	Point-of-Care Bedside Lung Ultrasound Examination Advanced Trial Protocol	https://ClinicalTrials.gov/show/NCT02403791	Completed	Nanjing Medical University	2015-03-31
NCT02282657	Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS	https://ClinicalTrials.gov/show/NCT02282657	Completed	European Society of Intensive Care Medicine	2017-07-31
NCT02273687	Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department	https://ClinicalTrials.gov/show/NCT02273687	Completed	Centre Hospitalier Universitaire de NÄ«mes	2017-09-29
NCT02252094	Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS	https://ClinicalTrials.gov/show/NCT02252094	Recruiting	National University Health System, Singapore	2019-12-31
NCT02027181	Automatic Administration of Oxygen During Respiratory Distress	https://ClinicalTrials.gov/show/NCT02027181	Completed	University Hospital, Brest	2014-10-31
NCT02166853	Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study)	https://ClinicalTrials.gov/show/NCT02166853	Completed	University Hospital, Clermont-Ferrand	2016-02-29
NCT02027129	Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO	https://ClinicalTrials.gov/show/NCT02027129	Completed	University of Athens	2016-10-31
NCT02106975	Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury	https://ClinicalTrials.gov/show/NCT02106975	Completed	Virginia Commonwealth University	2017-11-16
NCT02097641	Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START)	https://ClinicalTrials.gov/show/NCT02097641	Completed	University of California, San Francisco	2017-03-09
NCT02064140	Supported Ventilation in ARDS Patients	https://ClinicalTrials.gov/show/NCT02064140	Completed	University Medical Center Nijmegen	2014-11-30
NCT02058004	Does Cricoid Pressure Reduce the Risk of Aspiration?	https://ClinicalTrials.gov/show/NCT02058004	Completed	Mayo Clinic	2014-10-31
NCT01289600	Mechanical Ventilation and Respiratory Muscle Work of Breathing in Acute Respiratory Distress Syndrome (ARDS) Patients	https://ClinicalTrials.gov/show/NCT01289600	Completed	University Medical Center Nijmegen	2013-03-31
NCT01284452	Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01284452	Completed	Mahidol University	2014-12-31
NCT01274481	Iloprost Effects on Gas Exchange and Pulmonary Mechanics	https://ClinicalTrials.gov/show/NCT01274481	Completed	University of Oklahoma	2012-07-31
NCT01272882	Electrical Impedance Tomography (EIT) Monitoring in Adults With ALI or ARDS	https://ClinicalTrials.gov/show/NCT01272882	Completed	Christiana Care Health Services	2011-03-31
NCT04442958	Effectiveness of Convalescent Immune Plasma Therapy	https://ClinicalTrials.gov/show/NCT04442958	Completed	Bagcilar Training and Research Hospital	2020-06-15
NCT04369469	Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia	https://ClinicalTrials.gov/show/NCT04369469	Recruiting	Alexion Pharmaceuticals	2020-11-30
NCT04312009	Losartan for Patients With COVID-19 Requiring Hospitalization	https://ClinicalTrials.gov/show/NCT04312009	Recruiting	University of Minnesota	2021-04-01
NCT02439151	New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS	https://ClinicalTrials.gov/show/NCT02439151	Completed	Beijing Chao Yang Hospital	2020-06-25
NCT01899560	ELASTANCE: Prospective Physiological Study of Lung Elastance in Recruitment and Derecruitment in Early Onset Mechanically Ventilated ARDS Patients	https://ClinicalTrials.gov/show/NCT01899560	Completed	Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer	2013-06-30
NCT01883869	Targeting Platelet-Leukocyte Aggregates in Pneumonia With Ticagrelor	https://ClinicalTrials.gov/show/NCT01883869	Completed	University of Kentucky	2016-06-30
NCT01783821	LIPS-B: Lung Injury Prevention Study With Budesonide and Beta	https://ClinicalTrials.gov/show/NCT01783821	Completed	Mayo Clinic	2015-07-31
NCT01768949	Echocardiography Predictive of the Inefficacy and/or of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome.	https://ClinicalTrials.gov/show/NCT01768949	Completed	Centre Hospitalier Universitaire de Besancon	2017-01-31
NCT01743105	Reproductibility of TM-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in the ER	https://ClinicalTrials.gov/show/NCT01743105	Completed	Centre Hospitalier Universitaire de NÄ«mes	2014-01-31
NCT01731795	Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01731795	Completed	Dr. Negrin University Hospital	2019-02-12
NCT04153487	Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury	https://ClinicalTrials.gov/show/NCT04153487	Recruiting	Damanhour University	2020-12-31
NCT01683669	Effect of Variable PSV in Acute Lung Injury: Part I and Part II	https://ClinicalTrials.gov/show/NCT01683669	Completed	University of Genova	2016-12-31
NCT01680783	Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure	https://ClinicalTrials.gov/show/NCT01680783	Completed	University of Chicago	2016-05-31
NCT01659307	The Effect of Aspirin on REducing iNflammation in Human in Vivo Model of Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01659307	Recruiting	Belfast Health and Social Care Trust	2019-08-31
NCT01640990	A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT01640990	Completed	GlaxoSmithKline	2011-12-09
NCT01627613	Study in Intensive Care Patients to Investigate the Clinical Effect of Repetitive Orally Inhaled Doses of AP301 on Alveolar Liquid Clearance in Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01627613	Completed	Apeptico Forschung und Entwicklung GmbH	2014-05-31
NCT01600651	Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study)	https://ClinicalTrials.gov/show/NCT01600651	Completed	University Hospital, Clermont-Ferrand	2013-10-31
NCT01597635	The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01597635	Completed	GlaxoSmithKline	2014-10-01
NCT01585922	Noninvasive Positive Pressure Ventilation in Moderate Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01585922	Completed	Beijing Hospital	2016-12-31
NCT01581229	Early Use of Noninvasive Positive Pressure Ventilation for Intro-pulmonary Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01581229	Completed	Beijing Hospital	2016-12-31
NCT01552070	Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01552070	Completed	Chang Gung Memorial Hospital	2013-05-31
NCT01532024	Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs	https://ClinicalTrials.gov/show/NCT01532024	Completed	University of Edinburgh	2016-09-02
NCT01526382	Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01526382	Completed	Jinhua Central Hospital	2014-06-30
NCT01519258	Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS	https://ClinicalTrials.gov/show/NCT01519258	Completed	University of Sao Paulo General Hospital	2015-11-30
NCT01504893	Protective Ventilation With Low Tidal Volume Versus an Ultraprotective Ventilatory Strategy for One-lung Ventilation in Patients Undergoing Thoracic Anesthesia.	https://ClinicalTrials.gov/show/NCT01504893	Completed	Azienda Ospedaliera S. Maria della Misericordia	2016-08-31
NCT01504867	LIPS-A: Lung Injury Prevention Study With Aspirin	https://ClinicalTrials.gov/show/NCT01504867	Completed	Mayo Clinic	2015-09-30
NCT01502332	Intensive Alveolar Recruitment Protocol After Cardiac Surgery	https://ClinicalTrials.gov/show/NCT01502332	Completed	University of Sao Paulo	2014-02-28
NCT01474863	Citrulline in Severe Sepsis	https://ClinicalTrials.gov/show/NCT01474863	Completed	Vanderbilt University Medical Center	2016-03-31
NCT01470703	Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01470703	Completed	Assistance Publique - Hôpitaux de Paris	2017-07-31
NCT01438853	Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01438853	Completed	Altor BioScience	2006-07-31
NCT01434121	Ascorbic Acid (Vitamin C) Infusion in Human Sepsis	https://ClinicalTrials.gov/show/NCT01434121	Completed	Virginia Commonwealth University	2012-09-30
NCT01423864	Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01423864	Completed	National Taiwan University Hospital	2009-06-30
NCT01373905	Stepwise Positive End Expiratory Pressure Elevation For Lung Recruitment in Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01373905	Completed	University of Alexandria	2008-02-29
NCT01335932	Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure	https://ClinicalTrials.gov/show/NCT01335932	Completed	Fred Hutchinson Cancer Research Center	2016-06-17
NCT01320384	Clinical Effect of the Association of Noninvasive Ventilation and High Flow Nasal Oxygen Therapy in Resuscitation of Patients With Acute Lung Injury (FLORALI Study)	https://ClinicalTrials.gov/show/NCT01320384	Completed	Poitiers University Hospital	2013-07-31
NCT04447833	Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04447833	Recruiting	Uppsala University	2020-12-30
NCT04435535	Chest Physiotherapy in Tracheotomized Patients	https://ClinicalTrials.gov/show/NCT04435535	Completed	Linkoeping University	2017-03-31
NCT04434001	ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery	https://ClinicalTrials.gov/show/NCT04434001	Recruiting	IRCCS Policlinico S. Donato	2020-08-10
NCT04416139	Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19	https://ClinicalTrials.gov/show/NCT04416139	Recruiting	Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	2021-04-30
NCT04412057	Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury	https://ClinicalTrials.gov/show/NCT04412057	Recruiting	Cerecor Inc	2020-10-31
NCT04402866	TD-0903 for ALI Associated With COVID-19	https://ClinicalTrials.gov/show/NCT04402866	Recruiting	Theravance Biopharma	2020-10-31
NCT04402840	Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT04402840	Recruiting	West Virginia University	2020-07-31
NCT04402060	A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19	https://ClinicalTrials.gov/show/NCT04402060	Recruiting	Apellis Pharmaceuticals, Inc.	2020-11-30
NCT04395105	Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial	https://ClinicalTrials.gov/show/NCT04395105	Recruiting	Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno	2020-12-31
NCT04391140	Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS	https://ClinicalTrials.gov/show/NCT04391140	Recruiting	Hospital Universitari Vall d’Hebron Research Institute	2020-12-31
NCT04390139	Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19	https://ClinicalTrials.gov/show/NCT04390139	Recruiting	Banc de Sang i Teixits	2020-10-31
NCT04389840	Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure	https://ClinicalTrials.gov/show/NCT04389840	Recruiting	Chimerix	2021-02-28
NCT04388826	COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111	https://ClinicalTrials.gov/show/NCT04388826	Recruiting	Veru Inc.	2020-07-30
NCT04382391	Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms	https://ClinicalTrials.gov/show/NCT04382391	Recruiting	Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)	2020-09-01
NCT04378920	A Study of Trans Crocetin in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Disease (LEAF-4L7520/4L6715)	https://ClinicalTrials.gov/show/NCT04378920	Recruiting	Institut de Cancerologie Strasbourg Europe	2020-07-31
NCT04373200	Human Ab Response & immunoMONItoring of COVID-19 Patients	https://ClinicalTrials.gov/show/NCT04373200	Recruiting	Rennes University Hospital	2020-11-25
NCT04371393	MSCs in COVID-19 ARDS	https://ClinicalTrials.gov/show/NCT04371393	Recruiting	Icahn School of Medicine at Mount Sinai	2021-04-30
NCT04369599	Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q Vest for COVID-19	https://ClinicalTrials.gov/show/NCT04369599	Enrolling by invitation	Emory University	2021-03-31
NCT04366063	Mesenchymal Stem Cell Therapy for SARS-CoV-2-related Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04366063	Recruiting	Royan Institute	2020-06-06
NCT04361526	Pilot Study on Cytokine Filtration in COVID-19 ARDS	https://ClinicalTrials.gov/show/NCT04361526	Recruiting	Hospital Clinic of Barcelona	2020-07-31
NCT04359862	Sedation With Sevoflurane Versus Propofol in Patients With Acute Respiratory Distress Syndrome Caused by COVID19 Infection	https://ClinicalTrials.gov/show/NCT04359862	Recruiting	Fundación para la Investigación del Hospital Clínico de Valencia	2020-08-16
NCT04359251	Different PEEP Settings of COVID-19 Induced ARDS	https://ClinicalTrials.gov/show/NCT04359251	Completed	Southeast University, China	2020-03-25
NCT04357730	Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection	https://ClinicalTrials.gov/show/NCT04357730	Recruiting	Denver Health and Hospital Authority	2020-09-30
NCT04355728	Use of UC-MSCs for COVID-19 Patients	https://ClinicalTrials.gov/show/NCT04355728	Recruiting	University of Miami	2021-04-30
NCT04355364	Efficacy and Safety of Aerosolized Intra-tracheal Dornase Alfa Administration in Patients With COVID19-induced ARDS (COVIDORNASE)	https://ClinicalTrials.gov/show/NCT04355364	Recruiting	Fondation Ophtalmologique Adolphe de Rothschild	2020-08-21
NCT04352725	Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS	https://ClinicalTrials.gov/show/NCT04352725	Recruiting	Centre Hospitalier Intercommunal Aix-Pertuis	2020-11-30
NCT04351906	Low-flow Extracorporeal Carbon Dioxide Removal in COVID-19-associated Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04351906	Recruiting	University of Giessen	2020-07-31
NCT04350736	First in Human SAD and MAD Study of Inhaled TD-0903, a Potential Treatment for ALI Associated With COVID-19	https://ClinicalTrials.gov/show/NCT04350736	Recruiting	Theravance Biopharma	2020-06-30
NCT04350580	Polyvalent Immunoglobulin in COVID-19 Related ARds	https://ClinicalTrials.gov/show/NCT04350580	Recruiting	Centre Hospitalier St Anne	2020-06-30
NCT04347980	Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19	https://ClinicalTrials.gov/show/NCT04347980	Recruiting	Centre Chirurgical Marie Lannelongue	2020-06-30
NCT04335786	Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease	https://ClinicalTrials.gov/show/NCT04335786	Recruiting	Radboud University	2020-12-31
NCT04333368	Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS	https://ClinicalTrials.gov/show/NCT04333368	Recruiting	Assistance Publique - Hôpitaux de Paris	2020-08-31
NCT04331613	Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS	https://ClinicalTrials.gov/show/NCT04331613	Recruiting	Chinese Academy of Sciences	2020-12-31
NCT04328467	Pre-exposure Prophylaxis for SARS-Coronavirus-2	https://ClinicalTrials.gov/show/NCT04328467	Active, not recruiting	University of Minnesota	2020-08-31
NCT04325685	The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia	https://ClinicalTrials.gov/show/NCT04325685	Active, not recruiting	Northern State Medical University	2021-12-31
NCT04325061	Efficacy of Dexamethasone Treatment for Patients With ARDS Caused by COVID-19	https://ClinicalTrials.gov/show/NCT04325061	Recruiting	Dr. Negrin University Hospital	2020-10-30
NCT04321616	The Efficacy of Different Anti-viral Drugs in COVID 19 Infected Patients	https://ClinicalTrials.gov/show/NCT04321616	Recruiting	Oslo University Hospital	2020-08-31
NCT04289324	Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants	https://ClinicalTrials.gov/show/NCT04289324	Recruiting	Medical University of Vienna	2022-06-30
NCT04289194	Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04289194	Active, not recruiting	Histocell, S.L.	2021-07-31
NCT04133740	Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study	https://ClinicalTrials.gov/show/NCT04133740	Active, not recruiting	Aalborg University Hospital	2019-07-15
NCT04115709	Decision Support System to Evaluate VENTilation in ARDS	https://ClinicalTrials.gov/show/NCT04115709	Recruiting	Imperial College London	2021-03-30
NCT04106128	Prevalence, Impact and Reversibility of Acute Diaprhagmatic Dysfunction in Acute Respiratory Detresse	https://ClinicalTrials.gov/show/NCT04106128	Recruiting	Centre Hospitalier Universitaire de Nice	2020-10-05
NCT04070053	Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway	https://ClinicalTrials.gov/show/NCT04070053	Recruiting	University of Calgary	2021-01-31
NCT04028336	The Strategy of “Pulmonary Opening by Titration of Positive End-expiratory Pressure” Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients?	https://ClinicalTrials.gov/show/NCT04028336	Recruiting	Centre Hospitalier de Lens	2021-01-07
NCT04014218	Effect of Inhalation Sedation Compared With Propofol on the Sepsis-related Acute Respiratory Distress Syndrome Course	https://ClinicalTrials.gov/show/NCT04014218	Recruiting	Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy	2019-09-30
NCT03984175	Clinical Decision Support for Mechanical Ventilation of Patients With ARDS	https://ClinicalTrials.gov/show/NCT03984175	Recruiting	Intermountain Health Care, Inc.	2020-09-01
NCT03926533	Telehealth-Enhanced Patient-Oriented Recovery Trajectory After ICU	https://ClinicalTrials.gov/show/NCT03926533	Recruiting	Vanderbilt University	2021-06-30
NCT03909854	Pragmatic Investigation of Volume Targeted Ventilation-1	https://ClinicalTrials.gov/show/NCT03909854	Active, not recruiting	Wake Forest University Health Sciences	2019-11-12
NCT03905837	Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery	https://ClinicalTrials.gov/show/NCT03905837	Recruiting	Hospital General Universitario Gregorio Marañon	2021-05-28
NCT03896802	Hemodynamic Effects of PEEP in ARDS	https://ClinicalTrials.gov/show/NCT03896802	Recruiting	University of Milan	2019-12-31
NCT03818854	Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03818854	Recruiting	University of California, San Francisco	2023-07-01
NCT03807804	Efficacy and Safety Study of HLCM051(MultiStem®) for Pneumonic Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03807804	Recruiting	Healios K.K.	2020-12-31
NCT03799874	Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03799874	Active, not recruiting	Brigham and Women’s Hospital	2022-12-31
NCT03793842	Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03793842	Recruiting	University of Michigan	2021-01-31
NCT03764319	Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and VV-ECMO	https://ClinicalTrials.gov/show/NCT03764319	Recruiting	Medical University of Vienna	2020-05-06
NCT03753022	Effects of PEEP on Parameters of Tissue Perfusion in Patients Post Cardiac Surgery	https://ClinicalTrials.gov/show/NCT03753022	Active, not recruiting	Federal University of São Paulo	2019-12-31
NCT03736707	Selective High Frequency Oscillatory Ventilation (HFOV) for Neonates	https://ClinicalTrials.gov/show/NCT03736707	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2022-12-12
NCT03719937	Artificial Increase in Chest Wall Elastance as an Alternative to Prone Positioning in Moderate-to-severe ARDS.	https://ClinicalTrials.gov/show/NCT03719937	Recruiting	Catholic University of the Sacred Heart	2021-04-01
NCT03712215	STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT	https://ClinicalTrials.gov/show/NCT03712215	Recruiting	Universidade Metodista de Piracicaba	2019-01-31
NCT03651817	Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg	https://ClinicalTrials.gov/show/NCT03651817	Completed	Kocaeli University	2019-11-20
NCT03642002	The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU	https://ClinicalTrials.gov/show/NCT03642002	Recruiting	Icahn School of Medicine at Mount Sinai	2021-09-30
NCT03637530	a Study Conducted About a New Mode of Ventilation in Laparoscopic Surgeries	https://ClinicalTrials.gov/show/NCT03637530	Active, not recruiting	All India Institute of Medical Sciences, Rishikesh	2018-05-31
NCT03621293	Long Term Outcome on Brain and Lung of Different Oxygen Strategies in ARDS Patients	https://ClinicalTrials.gov/show/NCT03621293	Recruiting	Centre Hospitalier Universitaire de Besancon	2021-03-20
NCT03608592	Human Umbilical Cord Mesenchymal Stem Cells (MSCs) Therapy in ARDS	https://ClinicalTrials.gov/show/NCT03608592	Recruiting	Sun Yat-sen University	2020-08-01
NCT03552601	The Effect of Negatively Fluid Balancing Speed for ICU Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03552601	Recruiting	Qingdao University	2020-12-01
NCT04456361	Use of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Caused by COVID-19	https://ClinicalTrials.gov/show/NCT04456361	Active, not recruiting	Instituto de Medicina Regenerativa	2020-07-15
NCT03498807	A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients	https://ClinicalTrials.gov/show/NCT03498807	Completed	Far Eastern Memorial Hospital	2019-02-28
NCT03465085	Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS	https://ClinicalTrials.gov/show/NCT03465085	Completed	Beni-Suef University	2018-01-30
NCT01260259	Seattle Cardiorenal Remote Ischemic Preconditioning Trial	https://ClinicalTrials.gov/show/NCT01260259	Completed	Seattle Children’s Hospital	2013-08-31
NCT01239966	Pulmonary And Renal Support During Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01239966	Completed	Hôpital Européen Marseille	2014-12-31
NCT01194895	A Trial to Evaluate the Impact of Lung-protective Intervention in Patients Undergoing Esophageal Cancer Surgery	https://ClinicalTrials.gov/show/NCT01194895	Completed	Shanghai Zhongshan Hospital	2013-01-31
NCT01150864	Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial	https://ClinicalTrials.gov/show/NCT01150864	Completed	Università degli Studi dell’Insubria	2015-03-31
NCT01144585	Effects of Remote Ischemic Preconditioning and Postconditioning on Lung Injury During Cardiopulmonary Bypass	https://ClinicalTrials.gov/show/NCT01144585	Completed	Seoul National University Hospital	2010-11-30
NCT01119872	Pilot Study of Positive-End Expiratory Pressure in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01119872	Completed	Hospital Universitario Principe de Asturias	2007-12-31
NCT01114009	Effects of Recruitment Maneuvers in Early Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) Patients	https://ClinicalTrials.gov/show/NCT01114009	Completed	Chi Mei Medical Hospital	2011-12-31
NCT01050699	Sleep Intervention During Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01050699	Active, not recruiting	University of Arizona	2019-03-31
NCT00999713	CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients	https://ClinicalTrials.gov/show/NCT00999713	Completed	Milton S. Hershey Medical Center	2015-09-30
NCT00996840	SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS	https://ClinicalTrials.gov/show/NCT00996840	Completed	GlaxoSmithKline	2013-02-09
NCT00963066	NAV-ALI: Neurally Adjusted Ventilatory Assist in Patients Recovering Spontaneous Breathing After Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00963066	Completed	University Hospital, Caen	2009-11-30
NCT00958685	Safety Study of Feeding With Ginger Extract in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00958685	Completed	Shahid Beheshti University	2009-01-31
NCT00883948	Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study)	https://ClinicalTrials.gov/show/NCT00883948	Completed	National Heart, Lung, and Blood Institute (NHLBI)	2011-03-31
NCT00879606	Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00879606	Completed	Altor BioScience	2012-10-31
NCT03870009	Validation of a Semi-automatized Method to Detect Cyclic Hyperinflation on CT-scan in ARDS	https://ClinicalTrials.gov/show/NCT03870009	Recruiting	Hospices Civils de Lyon	2021-08-31
NCT00852605	Acute Lung Injury After Allogeneic Transplantation - Diagnosis and Early Treatment	https://ClinicalTrials.gov/show/NCT00852605	Completed	Technische Universität Dresden	2005-08-31
NCT04325906	Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS	https://ClinicalTrials.gov/show/NCT04325906	Recruiting	Rush University Medical Center	2020-08-31
NCT04311177	Losartan for Patients With COVID-19 Not Requiring Hospitalization	https://ClinicalTrials.gov/show/NCT04311177	Recruiting	University of Minnesota	2021-04-01
NCT03591796	Invasive Ventilation for Neonates With Acute Respiratory Distress Syndrome(ARDS)	https://ClinicalTrials.gov/show/NCT03591796	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2022-10-01
NCT00830284	Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00830284	Completed	Boston Children’s Hospital	2012-12-31
NCT04402879	CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals	https://ClinicalTrials.gov/show/NCT04402879	Recruiting	University of Calgary	2020-12-01
NCT04358939	Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19)	https://ClinicalTrials.gov/show/NCT04358939	Recruiting	University Hospital, Tours	2020-11-10
NCT01775774	Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01775774	Completed	University of California, San Francisco	2014-02-28
NCT01681225	EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures	https://ClinicalTrials.gov/show/NCT01681225	Completed	Beth Israel Deaconess Medical Center	2017-10-12
NCT04139733	Early Use of Prone Position in ECMO for Severe ARDS	https://ClinicalTrials.gov/show/NCT04139733	Recruiting	Beijing Chao Yang Hospital	2022-08-31
NCT03462849	Expiratory Flow Limitation Assessment	https://ClinicalTrials.gov/show/NCT03462849	Completed	Hospices Civils de Lyon	2019-05-02
NCT04365985	Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19	https://ClinicalTrials.gov/show/NCT04365985	Recruiting	William Beaumont Hospitals	2021-05-31
NCT04351243	A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE).	https://ClinicalTrials.gov/show/NCT04351243	Recruiting	Kinevant Sciences GmbH	2020-10-31
NCT04311697	Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure	https://ClinicalTrials.gov/show/NCT04311697	Recruiting	NeuroRx, Inc.	2020-08-31
NCT03896763	PROSpect: Prone and Oscillation Pediatric Clinical Trial	https://ClinicalTrials.gov/show/NCT03896763	Recruiting	University of Pennsylvania	2023-05-31
NCT04221737	Early Use of Airway Pressure Release Ventilation (APRV) in ARDS	https://ClinicalTrials.gov/show/NCT04221737	Recruiting	Hospital Civil de Guadalajara	2025-11-30
NCT01862016	Early Spontaneous Breathing in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01862016	Active, not recruiting	University Hospital, Angers	2017-12-16
NCT00789685	Safety, Tolerability and Preliminary Efficacy of FP-1201 in ALI and ARDS. Phase I/II	https://ClinicalTrials.gov/show/NCT00789685	Completed	Faron Pharmaceuticals Ltd	2011-09-30
NCT00786292	Evaluation of Variable Pressure Support Ventilation in the Therapy of Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00786292	Completed	Technische Universität Dresden	2012-09-30
NCT00747045	Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients	https://ClinicalTrials.gov/show/NCT00747045	Completed	University of California, San Diego	2011-03-31
NCT00655928	Modulation of Lung Injury Complicating Lung Resection	https://ClinicalTrials.gov/show/NCT00655928	Completed	Imperial College London	2009-07-31
NCT00646152	Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study	https://ClinicalTrials.gov/show/NCT00646152	Completed	National Institutes of Health Clinical Center (CC)	2009-12-16
NCT00644930	Non-Invasive Positive Pressure Ventilation and Adult Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT00644930	Completed	Eskisehir Osmangazi University	2005-09-30
NCT00624650	Hemodynamics and Extravascular Lung Water in Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00624650	Completed	Oregon Health and Science University	2011-01-31
NCT00605696	Early Insulin and Development of ARDS	https://ClinicalTrials.gov/show/NCT00605696	Completed	Albert Einstein College of Medicine	2011-12-31
NCT00568659	The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position	https://ClinicalTrials.gov/show/NCT00568659	Completed	Policlinico Hospital	2010-11-30
NCT00559130	Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis	https://ClinicalTrials.gov/show/NCT00559130	Completed	MedaSorb Technologies, Inc	2011-04-30
NCT00538928	Extrapulmonary Interventional Ventilatory Support in Severe Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT00538928	Completed	University of Regensburg	2011-01-31
NCT00538161	Effect of Low Tidal Volume Ventilation in Improving Oxygenation and Thus Reducing Acute Lung Injury in the Cardiac Surgical Patient	https://ClinicalTrials.gov/show/NCT00538161	Completed	Beth Israel Deaconess Medical Center	2009-10-31
NCT00527813	Effect of Prone Positioning on Mortality in Patients With Severe and Persistent Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00527813	Completed	Hospices Civils de Lyon	2011-08-31
NCT00498251	Prevention of Lung Edema After Thoracic Surgery	https://ClinicalTrials.gov/show/NCT00498251	Completed	University Hospital, Geneva	NA
NCT00474656	The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study	https://ClinicalTrials.gov/show/NCT00474656	Completed	Canadian Critical Care Trials Group	2008-07-31
NCT00465309	Protective Ventilation With Carbon Dioxide (CO2) -Removal Technique in Patients With Adult Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT00465309	Completed	University of Turin, Italy	NA
NCT00455767	Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients	https://ClinicalTrials.gov/show/NCT00455767	Completed	Debiopharm International SA	2007-09-30
NCT00431158	ARDSnet Protocol vs. Open Lung Approach in ARDS	https://ClinicalTrials.gov/show/NCT00431158	Completed	Massachusetts General Hospital	2012-09-30
NCT00416260	Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00416260	Completed	University of Athens	2007-09-30
NCT00399581	Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00399581	Completed	Johns Hopkins University	2009-05-31
NCT00351533	A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI)	https://ClinicalTrials.gov/show/NCT00351533	Completed	University of Washington	2009-01-31
NCT00314548	Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension	https://ClinicalTrials.gov/show/NCT00314548	Completed	Aga Khan University	2009-07-31
NCT00295269	Corticosteroids as Rescue Therapy for the Late Phase of Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00295269	Completed	National Heart, Lung, and Blood Institute (NHLBI)	NA
NCT00290602	Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00290602	Completed	National Cancer Center, Korea	NA
NCT00284102	PEEP Test and Gas Exchange in ALI/ARDS Patients	https://ClinicalTrials.gov/show/NCT00284102	Completed	Policlinico Hospital	2008-04-30
NCT00281268	Fluids and Catheters Treatment Trial (FACTT) - ARDS Clinical Research Network	https://ClinicalTrials.gov/show/NCT00281268	Completed	National Heart, Lung, and Blood Institute (NHLBI)	2005-10-31
NCT00267241	Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) Patients	https://ClinicalTrials.gov/show/NCT00267241	Completed	Policlinico Hospital	2014-11-30
NCT00240487	Nitric Oxide Administration for Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00240487	Completed	Children’s Hospital of Philadelphia	2008-09-30
NCT00236262	Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00236262	Completed	Assistance Publique - Hôpitaux de Paris	NA
NCT00219375	Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan	https://ClinicalTrials.gov/show/NCT00219375	Completed	Ono Pharmaceutical Co. Ltd	2007-07-31
NCT00217880	Significance of Biological Markers in Patients With Acute Lung Injury/Acute Respiratory Disease	https://ClinicalTrials.gov/show/NCT00217880	Completed	University of Michigan	2009-04-30
NCT00201409	A Randomized Trial of GM-CSF in Patients With ALI/ARDS	https://ClinicalTrials.gov/show/NCT00201409	Completed	University of Michigan	2009-05-31
NCT00188058	Comparison of 2 Strategies of Adjustment of Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00188058	Completed	University Hospital, Angers	2006-01-31
NCT00182195	Lung Open Ventilation to Decrease Mortality in the Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00182195	Completed	McMaster University	NA
NCT00159939	Prone-Supine Study II: The Effect of Prone Positioning for Patients Affected by Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00159939	Completed	Policlinico Hospital	2008-06-30
NCT00149513	Post-Hospital Case Management to Improve Clinical Outcomes in Individuals Requiring Mechanical Ventilation	https://ClinicalTrials.gov/show/NCT00149513	Completed	University of Washington	2009-02-28
NCT00143468	The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients	https://ClinicalTrials.gov/show/NCT00143468	Completed	Policlinico Hospital	2007-03-31
NCT00141726	Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant	https://ClinicalTrials.gov/show/NCT00141726	Completed	University of Michigan Rogel Cancer Center	2008-07-31
NCT00133614	Prone Positioning in Pediatric Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00133614	Completed	National Institute of Nursing Research (NINR)	NA
NCT00127491	Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00127491	Completed	Beth Israel Deaconess Medical Center	2007-08-31
NCT00113685	Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury	https://ClinicalTrials.gov/show/NCT00113685	Completed	University of Washington	NA
NCT00094406	Carbon Monoxide to Prevent Lung Inflammation	https://ClinicalTrials.gov/show/NCT00094406	Completed	National Institutes of Health Clinical Center (CC)	2010-03-11
NCT00036062	A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00036062	Completed	Eli Lilly and Company	NA
NCT00029328	Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation	https://ClinicalTrials.gov/show/NCT00029328	Completed	FDA Office of Orphan Products Development	NA
NCT00000579	Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)	https://ClinicalTrials.gov/show/NCT00000579	Completed	National Heart, Lung, and Blood Institute (NHLBI)	NA
NCT00000574	Ibuprofen in Sepsis Study	https://ClinicalTrials.gov/show/NCT00000574	Completed	Vanderbilt University	NA
NCT00000572	Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00000572	Completed	Intermountain Health Care, Inc.	1991-04-30

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04460859	RecruitmEnt Assessed by eleCtRical Impedance Tomography	https://ClinicalTrials.gov/show/NCT04460859	Recruiting	St. Michael’s Hospital, Toronto	2021-12-31
NCT04457739	Assessment of Preload Responsiveness in ARDS Patients During Prone Position	https://ClinicalTrials.gov/show/NCT04457739	Recruiting	Bicetre Hospital	2020-12-31
NCT04383730	Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19)	https://ClinicalTrials.gov/show/NCT04383730	Recruiting	University Hospital, Clermont-Ferrand	2020-11-30
NCT03379207	Innate Immune Response During Community Acquired Pneumonia	https://ClinicalTrials.gov/show/NCT03379207	Recruiting	University Hospital, Tours	2022-01-09
NCT03871166	Hemoglobin Concentration in Patients With an Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03871166	Recruiting	Charite University, Berlin, Germany	2019-10-01
NCT03317431	the Effect of Dopamine on Mechanical Ventilation Induced Lung Injury	https://ClinicalTrials.gov/show/NCT03317431	Completed	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	2017-10-22
NCT03315702	Effect of Mechanical Ventilation on Plasma Concentration Level of R-spondin Proteins	https://ClinicalTrials.gov/show/NCT03315702	Completed	Xinhua Hospital, Shanghai Jiao Tong University School of Medicine	2017-10-15
NCT03236272	Establishment of a Biomarkers-based Early Warning System of Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03236272	Recruiting	Third Military Medical University	2020-12-31
NCT03227289	Acute Respiratory Distress Syndrome(ARDS) in Neonates	https://ClinicalTrials.gov/show/NCT03227289	Recruiting	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2018-07-30
NCT03225807	Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure	https://ClinicalTrials.gov/show/NCT03225807	Recruiting	Intermountain Health Care, Inc.	2020-07-31
NCT03188770	Practice of Ventilation in Middle-Income Countries	https://ClinicalTrials.gov/show/NCT03188770	Completed	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	2018-11-29
NCT03179709	Provider Perceptions of Neuromuscular Blockade in ARDS	https://ClinicalTrials.gov/show/NCT03179709	Completed	University of Pittsburgh	2018-03-18
NCT03076983	Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time	https://ClinicalTrials.gov/show/NCT03076983	Completed	Drägerwerk AG & Co. KGaA	2018-04-12
NCT03038906	Effect of Randomization to Neuromuscular Blockade on Physical Functional Impairment and Recovery in ARDS	https://ClinicalTrials.gov/show/NCT03038906	Recruiting	University of Washington	2020-03-31
NCT03021824	Severe ARDS: Generating Evidence	https://ClinicalTrials.gov/show/NCT03021824	Completed	Montefiore Medical Center	2017-04-30
NCT02962505	Continuous Regional Analysis Device for Neonate Lung	https://ClinicalTrials.gov/show/NCT02962505	Completed	University of Schleswig-Holstein	2019-03-03
NCT02961166	Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients	https://ClinicalTrials.gov/show/NCT02961166	Completed	University Hospital Tuebingen	2016-01-31
NCT02944279	Neutrophil Elastase and Elafin as Prognostic Biomarker for Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02944279	Completed	Peking University Third Hospital	2014-08-31
NCT02889770	Dead Space Monitoring With Volumetric Capnography in ARDS Patients	https://ClinicalTrials.gov/show/NCT02889770	Completed	Hospital Italiano de Buenos Aires	2015-10-31
NCT02842788	Prevalence of Prone Positioning Use in ARDS Patients	https://ClinicalTrials.gov/show/NCT02842788	Completed	Hospices Civils de Lyon	2017-01-31
NCT02836444	Stratification of the Acute Respiratory Distress Syndrome - A Second Phase Study	https://ClinicalTrials.gov/show/NCT02836444	Completed	Dr. Negrin University Hospital	2017-05-01
NCT02732041	Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02732041	Completed	Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno	2018-11-22
NCT02711930	Effect of Prone Positioning on Intra-ocular Pressure in ARDS Patients	https://ClinicalTrials.gov/show/NCT02711930	Completed	Sanjay Gandhi Postgraduate Institute of Medical Sciences	2017-07-24
NCT02664090	Hemodynamic Assessment With Trans-esophageal Doppler (TED) During Prone Ventilation in ARDS Patients	https://ClinicalTrials.gov/show/NCT02664090	Completed	Sanjay Gandhi Postgraduate Institute of Medical Sciences	2017-01-18
NCT02638844	Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02638844	Completed	Central Hospital, Nancy, France	2017-07-31
NCT02606240	Low-Flow CO2 Removal for Mild to Moderate ARDS With PRISMALUNG	https://ClinicalTrials.gov/show/NCT02606240	Completed	Groupe Hospitalier Pitie-Salpetriere	2017-06-30
NCT02545621	A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study	https://ClinicalTrials.gov/show/NCT02545621	Completed	University Hospital, Clermont-Ferrand	2016-09-30
NCT02490215	Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs	https://ClinicalTrials.gov/show/NCT02490215	Completed	Peking Union Medical College Hospital	2015-08-31
NCT02475694	Acute Lung Injury After Cardiac Surgery: Pathogenesis	https://ClinicalTrials.gov/show/NCT02475694	Completed	Aalborg University Hospital	2009-03-31
NCT02415738	Changes in Cerebral Oxygenation During the Prone Position in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02415738	Completed	Centre Hospitalier Bretagne Atlantique	2017-02-28
NCT02288949	Stratification of the Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02288949	Completed	Dr. Negrin University Hospital	2015-07-31
NCT02265198	Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02265198	Completed	Wake Forest University Health Sciences	2015-03-31
NCT02247700	Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography	https://ClinicalTrials.gov/show/NCT02247700	Completed	Boston Children’s Hospital	2018-11-04
NCT02232841	Electrical Impedance Imaging of Patients on Mechanical Ventilation	https://ClinicalTrials.gov/show/NCT02232841	Completed	Colorado State University	2016-08-31
NCT02214576	High Flow Nasal Canula Oxygen Helps Preoxygenate ARDS Patients	https://ClinicalTrials.gov/show/NCT02214576	Completed	Hôpital Louis Mourier	2015-08-31
NCT02184208	Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System.	https://ClinicalTrials.gov/show/NCT02184208	Completed	Boston Children’s Hospital	2016-12-30
NCT02178982	Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02178982	Completed	Southeast University, China	2015-06-30
NCT02083393	Changes of Dendritic Cells in Acute Lung Injury	https://ClinicalTrials.gov/show/NCT02083393	Completed	Southeast University, China	2014-12-31
NCT02070536	Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients	https://ClinicalTrials.gov/show/NCT02070536	Completed	University Hospital, Clermont-Ferrand	2016-03-31
NCT01270295	Soluble Forms and Ligands of RAGE in ALI/ARDS (SoLiRAGE).	https://ClinicalTrials.gov/show/NCT01270295	Completed	University Hospital, Clermont-Ferrand	2013-01-31
NCT02019095	Clinical and Biological Markers in Acute Respiratory Failure	https://ClinicalTrials.gov/show/NCT02019095	Completed	University of Athens	2014-12-31
NCT02010073	Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE	https://ClinicalTrials.gov/show/NCT02010073	Completed	European Society of Intensive Care Medicine	2014-08-31
NCT01926093	Low Dose Lung CT Scan for Quantitative Analysis in ARDS Patients	https://ClinicalTrials.gov/show/NCT01926093	Completed	Policlinico Hospital	2013-05-31
NCT01922557	Thoracic Fluid Content and Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01922557	Completed	National Taiwan University Hospital	2011-01-31
NCT01878552	Energy Load in Patients With Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01878552	Completed	Policlinico Hospital	2014-08-31
NCT01854424	Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS	https://ClinicalTrials.gov/show/NCT01854424	Completed	Assistance Publique - Hôpitaux de Paris	2016-07-31
NCT04262440	The Effect of Caloric Supplement in the Clinical Outcomes in Acute Lung Injury Patients	https://ClinicalTrials.gov/show/NCT04262440	Recruiting	Taichung Veterans General Hospital	2022-12-31
NCT01714583	The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol	https://ClinicalTrials.gov/show/NCT01714583	Completed	Yale University	2012-09-30
NCT01704066	Interobserver Variation in Applying a Radiographic Definition for Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01704066	Completed	Society of Critical Care Medicine, China	2012-12-31
NCT01677130	Standardized Application of High Frequency Oscillatory Ventilation in the Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01677130	Completed	Southeast University, China	2014-12-31
NCT01670747	Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT01670747	Completed	Policlinico Hospital	2015-03-31
NCT01666834	Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China	https://ClinicalTrials.gov/show/NCT01666834	Completed	Southeast University, China	2013-05-31
NCT01628523	Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study	https://ClinicalTrials.gov/show/NCT01628523	Completed	Washington University School of Medicine	2013-08-31
NCT01601223	Local Assessment of Ventilatory Management During General Anesthesia for Surgery	https://ClinicalTrials.gov/show/NCT01601223	Completed	European Society of Anaesthesiology	2013-05-31
NCT01486342	PET Imaging in Patients at Risk for Acute Lung Injury	https://ClinicalTrials.gov/show/NCT01486342	Completed	Washington University School of Medicine	2012-10-31
NCT01478217	PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment	https://ClinicalTrials.gov/show/NCT01478217	Completed	Sisters of Mercy University Hospital	2011-11-30
NCT01468142	Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure	https://ClinicalTrials.gov/show/NCT01468142	Completed	Karolinska University Hospital	2016-12-31
NCT01450527	Etiology and Outcomes of Tropical Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01450527	Completed	All India Institute of Medical Sciences, New Delhi	2012-06-30
NCT01435889	Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01435889	Completed	University Hospital, Lille	2014-10-31
NCT01322295	Human Bronchial Microdialysis in Open Aortic Aneurysm Repair	https://ClinicalTrials.gov/show/NCT01322295	Completed	Norwegian University of Science and Technology	2011-11-30
NCT01321398	Transpulmonary Pressure Gradients in High Frequency Oscillation	https://ClinicalTrials.gov/show/NCT01321398	Completed	University of British Columbia	2011-07-31
NCT04443491	Comparison of Esophageal and Central Venous Pressure for Estimating Transpulmonary Pressure Changes	https://ClinicalTrials.gov/show/NCT04443491	Completed	University of Siena	2019-03-31
NCT04435080	Physical Rehabilitation in ICU in ARDS Patients With COVID-19	https://ClinicalTrials.gov/show/NCT04435080	Completed	Koç University	2020-06-11
NCT04411459	Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04411459	Recruiting	Azienda Usl di Bologna	2020-06-30
NCT04408326	Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04408326	Recruiting	Guy’s and St Thomas’ NHS Foundation Trust	2021-05-01
NCT04388813	Predictors of Severe COVID-19 Outcomes	https://ClinicalTrials.gov/show/NCT04388813	Recruiting	Verily Life Sciences LLC	2021-02-28
NCT04386720	Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrom and With or Without Covid 19.	https://ClinicalTrials.gov/show/NCT04386720	Recruiting	University Hospital, Bordeaux	2021-05-25
NCT04385004	Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU	https://ClinicalTrials.gov/show/NCT04385004	Recruiting	University Hospital, Strasbourg, France	2020-07-31
NCT04405817	Outcome of Patients Treated With ECLS	https://ClinicalTrials.gov/show/NCT04405817	Recruiting	Nanjing Medical University	2025-12-31
NCT04376905	Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19)	https://ClinicalTrials.gov/show/NCT04376905	Recruiting	University Hospital, Montpellier	2020-09-01
NCT04370249	Construction of a Composite Clinical-echo Score Predictive of a Risk of Short-term Aggravation of Respiratory Impairment in Patients Suspected of Covid-19	https://ClinicalTrials.gov/show/NCT04370249	Recruiting	Nantes University Hospital	2020-06-30
NCT02965079	Registry on the EXperience of Extracorporeal CO2 Removal in Intensive Care Units	https://ClinicalTrials.gov/show/NCT02965079	Recruiting	Rexecor	2020-01-31
NCT04337190	Impact of Angiotensin II Receptor Blockers Treatment in Patients With COVID 19 (COVID-ARA2)	https://ClinicalTrials.gov/show/NCT04337190	Recruiting	University Hospital, Angers	2020-10-06
NCT04319965	Complications Related to Transpulmonary Thermodilution	https://ClinicalTrials.gov/show/NCT04319965	Recruiting	Bicetre Hospital	2021-03-31
NCT04316884	Mechanisms for Organ Dysfunction in Covid-19	https://ClinicalTrials.gov/show/NCT04316884	Recruiting	Uppsala University	2020-12-31
NCT04157946	The Role of Morphological Phenotype in ARDS	https://ClinicalTrials.gov/show/NCT04157946	Completed	Hospital El Cruce	2019-07-10
NCT04154007	Acute Kidney Injury in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04154007	Completed	Zagazig University	2019-03-30
NCT04133558	Pulmonary Microbiota and ARDS Mortality	https://ClinicalTrials.gov/show/NCT04133558	Recruiting	University of Bordeaux	2020-11-01
NCT04113434	Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04113434	Recruiting	Children’s Hospital of Philadelphia	2023-01-31
NCT04079426	Tetracycline to Limit the Innate Immune Response in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04079426	Recruiting	University of Bonn	2021-01-31
NCT04078984	Driving Pressure as a Predictor of Mechanical Ventilation Weaning Time on Post-ARDS Patients in Pressure Support Ventilation.	https://ClinicalTrials.gov/show/NCT04078984	Recruiting	University Hospital, Bordeaux	2020-10-27
NCT04046380	A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies	https://ClinicalTrials.gov/show/NCT04046380	Recruiting	Changhua Christian Hospital	2021-06-30
NCT04009330	Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04009330	Recruiting	Queen’s University, Belfast	2021-06-30
NCT03969914	PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury	https://ClinicalTrials.gov/show/NCT03969914	Recruiting	Università degli Studi di Ferrara	2020-05-01
NCT03955887	Mitochondrial Dysfunction of Alveolar and Circulating Immune Cells During Acute Respiratory Distress Syndrome: Impact of Infectious Aggression and Alveolar Stretching as a Result of Mechanical Ventilation.	https://ClinicalTrials.gov/show/NCT03955887	Recruiting	Centre Hospitalier Universitaire Dijon	2021-01-31
NCT03946189	Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03946189	Completed	American University of Beirut Medical Center	2019-05-01
NCT03946150	PaO2/FiO2*PEEP (P/FP) Ratio and Mortality in Acute Respiratory Distress Syndrome.	https://ClinicalTrials.gov/show/NCT03946150	Completed	National University Health System, Singapore	2019-05-05
NCT03937947	Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study	https://ClinicalTrials.gov/show/NCT03937947	Recruiting	NHS Lothian	2020-10-31
NCT03920189	Echocardiographic Evaluation in ARDS Patients	https://ClinicalTrials.gov/show/NCT03920189	Recruiting	University of Milan	2020-09-01
NCT03828630	Lung Ultrasound to Detect Pulmonary Complications in Critically Ill Parturients	https://ClinicalTrials.gov/show/NCT03828630	Completed	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	2019-02-27
NCT03766204	The Role of Circulating CircRNAs and MicroRNAs in Acute Lung Injury	https://ClinicalTrials.gov/show/NCT03766204	Recruiting	Changhai Hospital	2023-12-31
NCT03763773	Prediction of Outcomes With a Miniaturized Transesophageal Echocardiography Probe in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03763773	Recruiting	University Hospital, Lille	2021-05-31
NCT03709199	Long Term Follow up of Children Enrolled in the REDvent Study	https://ClinicalTrials.gov/show/NCT03709199	Recruiting	Children’s Hospital Los Angeles	2023-01-01
NCT03662230	Incidence and Severity of Acute Respiratory Distress Syndrome (ARDS) in the French Wounded Soldiers	https://ClinicalTrials.gov/show/NCT03662230	Completed	Direction Centrale du Service de Santé des Armées	2019-11-07
NCT03654352	The ASTERS Study: Assessing the Role of Sphingolipids in AcuTE Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03654352	Recruiting	University of Kentucky	2020-12-31
NCT03641690	Serum and Bronchoalveolar Inflammatory Parameters in Patients With Severe Adult Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT03641690	Completed	Centre Hospitalier Universitaire, Amiens	2017-12-01
NCT03539783	Identifying PARDS Endotypes	https://ClinicalTrials.gov/show/NCT03539783	Recruiting	Children’s Hospital Medical Center, Cincinnati	2024-03-31
NCT03504176	Pediatric Acute Respiratory Distress Syndrome Ventilation Bundle	https://ClinicalTrials.gov/show/NCT03504176	Completed	KK Women’s and Children’s Hospital	2020-05-12
NCT03424798	Measuring Heart and Lung Function in Critical Care	https://ClinicalTrials.gov/show/NCT03424798	Recruiting	University of Oxford	2019-09-30
NCT03415529	Impact of Arterial CO2 Tension on Management and Outcome in Patients With Acute Hypoxemic Respirator Failure and ARDS	https://ClinicalTrials.gov/show/NCT03415529	Completed	European Society of Intensive Care Medicine	2018-09-30
NCT01256333	Optimization of Arterial Oxygen Transport by Positive End-expiratory Pressure Variation in Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT01256333	Completed	Rennes University Hospital	NA
NCT01187004	Extracardiac Complications After Cardiac Surgery	https://ClinicalTrials.gov/show/NCT01187004	Completed	University of Turin, Italy	2008-12-31
NCT01167621	Changes in Refractory Acute Respiratory Distress Syndrome (ARDS) Patients Under High Frequency Oscillation-ventilation	https://ClinicalTrials.gov/show/NCT01167621	Completed	Centre Hospitalier Universitaire de la Réunion	2012-09-30
NCT01161901	Impact of Inflammation Biomarkers on the Acute Respiratory Distress Syndrome (ARDS) Definition	https://ClinicalTrials.gov/show/NCT01161901	Completed	University Hospital, Clermont-Ferrand	2011-11-30
NCT01159392	Alveolar Recruitment in Brain Injury	https://ClinicalTrials.gov/show/NCT01159392	Completed	Hospital Clinic of Barcelona	NA
NCT01142544	Incidence of Acute Lung Injury in Children	https://ClinicalTrials.gov/show/NCT01142544	Completed	Dr. Negrin University Hospital	2011-02-28
NCT01105663	Pharmacologic Impact on Sedation Assessments	https://ClinicalTrials.gov/show/NCT01105663	Completed	Children’s Hospital of Philadelphia	2013-12-31
NCT01102322	Factors Associated With the Use of Lung Protective Ventilation Strategy (LPV) in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Intensive Care Unit (ICU)	https://ClinicalTrials.gov/show/NCT01102322	Completed	National Taiwan University Hospital	2011-01-31
NCT01089400	Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage	https://ClinicalTrials.gov/show/NCT01089400	Completed	Institut National de la Santé Et de la Recherche Médicale, France	NA
NCT01078831	Intrabronchial Airway Pressures in Intubated Patients During Bronchoscopy	https://ClinicalTrials.gov/show/NCT01078831	Completed	Oslo University Hospital	2010-04-30
NCT00980915	Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00980915	Active, not recruiting	Mayo Clinic	2020-12-31
NCT00889772	Lung Injury Prediction Study	https://ClinicalTrials.gov/show/NCT00889772	Completed	Mayo Clinic	2010-02-28
NCT04378582	Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU	https://ClinicalTrials.gov/show/NCT04378582	Recruiting	University of Sao Paulo General Hospital	2020-08-30
NCT03351920	Ventilation’s Parameters Applied in Emergency Medicine. A Prospective Observational Study	https://ClinicalTrials.gov/show/NCT03351920	Completed	Poitiers University Hospital	2019-07-22
NCT00826072	Inflammatory Genetic Polymorphism and Acute Lung Injury After Cardiac Surgery	https://ClinicalTrials.gov/show/NCT00826072	Completed	Changhai Hospital	2008-11-30
NCT00825357	Biological Markers to Identify Early Sepsis and Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00825357	Completed	Chimei Medical Center	2011-08-31
NCT03753412	Recovery From ICUAW Following Severe Respiratory and Cardiac Failure	https://ClinicalTrials.gov/show/NCT03753412	Recruiting	Barts & The London NHS Trust	2020-08-01
NCT04449081	Knowledge, Attitude and Practice of Dental Students About COVID-19	https://ClinicalTrials.gov/show/NCT04449081	Completed	Melaka Manipal Medical College	2020-06-10
NCT00811629	Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients	https://ClinicalTrials.gov/show/NCT00811629	Completed	University Hospital, Clermont-Ferrand	2009-07-31
NCT04383678	Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT04383678	Recruiting	Helsinki University Central Hospital	2020-12-31
NCT04350710	Description of Respiratory Mechanics in Patients With SARS-CoV-2 Associated ARDS	https://ClinicalTrials.gov/show/NCT04350710	Recruiting	University Hospital, Angers	2020-04-20
NCT02739438	The Study of ELEctronic Cigarette Toxicity in a Human Model in Vivo Model of Inflammation and Vascular Dysfunction	https://ClinicalTrials.gov/show/NCT02739438	Recruiting	Queen’s University, Belfast	2019-12-31
NCT02549222	A Open Label, Post Marketing Surveillance Study Following Transfusion of INTERCEPT Platelet Components	https://ClinicalTrials.gov/show/NCT02549222	Enrolling by invitation	Cerus Corporation	2020-09-30
NCT02457741	Validation of a Simple Approach to Estimate Alveolar Recruitability in ARDS Patients	https://ClinicalTrials.gov/show/NCT02457741	Completed	St. Michael’s Hospital, Toronto	2017-12-31
NCT02201446	The Role of Circulating Soluble CD74 in Acute Lung Injury	https://ClinicalTrials.gov/show/NCT02201446	Completed	Changhai Hospital	2014-11-30
NCT03715647	Correlation of Survival in Puerperae by Electrical Impedance Tomography	https://ClinicalTrials.gov/show/NCT03715647	Completed	Amazon University	2017-12-31
NCT04411368	Impact of Respiratory Virus in Critically Ill Patients With Acute Respiratory Failure	https://ClinicalTrials.gov/show/NCT04411368	Recruiting	Seoul St. Mary’s Hospital	2022-12-31
NCT00736892	Incidence of Acute Lung Injury: The Alien Study	https://ClinicalTrials.gov/show/NCT00736892	Completed	Villar, Jesus, M.D.	2010-03-31
NCT00719446	Evaluating Health Outcomes and QOL After ALI Among Participants of the ALTA, OMEGA, EDEN, and SAILS ARDS Network Trials	https://ClinicalTrials.gov/show/NCT00719446	Completed	Johns Hopkins University	2014-10-31
NCT00682942	How to Predict Lung Recruitment at the Bedside in Patients Affected by Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS)	https://ClinicalTrials.gov/show/NCT00682942	Completed	Policlinico Hospital	2011-06-30
NCT00673517	The Effect of High Frequency Oscillation on Biological Markers of Lung Injury	https://ClinicalTrials.gov/show/NCT00673517	Completed	St. Michael’s Hospital, Toronto	2008-11-30
NCT00659152	Morphofunctional Lung Analysis by Positron Emission Tomography	https://ClinicalTrials.gov/show/NCT00659152	Completed	Policlinico Hospital	2013-12-31
NCT00557414	Serial Changes of Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) Levels in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00557414	Completed	National Taiwan University Hospital	NA
NCT00548795	Viral-Related Neutrophil Response and Condition Severity in People With ARDS	https://ClinicalTrials.gov/show/NCT00548795	Completed	National Jewish Health	2011-01-31
NCT00521625	Epidemiologic Multicenter Study on Mechanical Ventilation Management in Children With Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00521625	Completed	St. Justine’s Hospital	NA
NCT00458926	Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care	https://ClinicalTrials.gov/show/NCT00458926	Active, not recruiting	Tufts Medical Center	2009-12-31
NCT00446706	Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT00446706	Completed	Texas Tech University Health Sciences Center, El Paso	2007-04-30
NCT00440882	Changes of Transforming Growth Factor b1 and Procollagen III in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00440882	Completed	Assistance Publique Hopitaux De Marseille	NA
NCT00435110	Effects of PEEP and FIO2 in ALI and ARDS	https://ClinicalTrials.gov/show/NCT00435110	Completed	Instituto Canario de Investigacion Biomedica	NA
NCT00819871	Nuclear Factor Kappa-B (NFKB1) Polymorphism and Organ Injury After Cardiac Surgery	https://ClinicalTrials.gov/show/NCT00819871	Completed	Changhai Hospital	2008-10-31
NCT00300248	Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00300248	Completed	Johns Hopkins University	2012-10-31
NCT00258518	Respiratory Mechanics and Pleural Effusion	https://ClinicalTrials.gov/show/NCT00258518	Completed	Policlinico Hospital	2011-06-30
NCT00234767	Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT00234767	Completed	University of Pittsburgh	2007-08-31
NCT00157144	Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005	https://ClinicalTrials.gov/show/NCT00157144	Completed	Bayside Health	2006-08-31
NCT00155779	ACE Gene Polymorphism and ARDS Outcome	https://ClinicalTrials.gov/show/NCT00155779	Completed	National Taiwan University Hospital	NA
NCT00142376	Short Term Outcomes of Children With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT00142376	Completed	Nationwide Children’s Hospital	NA
NCT00006496	Molecular Epidemiology of ARDS	https://ClinicalTrials.gov/show/NCT00006496	Recruiting	Massachusetts General Hospital	2022-08-31
NCT00005318	ARDS - Clinical Epidemiology and the Role of the Inflammatory Response - SCOR in Acute Lung Injury	https://ClinicalTrials.gov/show/NCT00005318	Completed	University of Minnesota	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT04457505	One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19	https://ClinicalTrials.gov/show/NCT04457505	Recruiting	Consorcio Centro de Investigación Biomédica en Red, M.P.	2021-05-31
NCT03311165	Epidemiological Study of Neonatal Acute Respiratory Distress Syndrome (ARDS)	https://ClinicalTrials.gov/show/NCT03311165	Completed	Daping Hospital and the Research Institute of Surgery of the Third Military Medical University	2019-06-30
NCT02799940	Abnormalities in Lung Computed Tomography and Physiological Alterations in Patients With Acute Respiratory Distress Syndrome	https://ClinicalTrials.gov/show/NCT02799940	Completed	Hospital Regional Rio Gallegos	2019-05-19
NCT02613377	Transfusion-related Acute Lung Injury: a Prospective Cohort Study in Critically Ill Children	https://ClinicalTrials.gov/show/NCT02613377	Active, not recruiting	St. Justine’s Hospital	2020-01-31
NCT02492204	The Role of IL33/ST2 Axis in ARDS Patients	https://ClinicalTrials.gov/show/NCT02492204	Completed	Hospital Universitari Vall d’Hebron Research Institute	2015-07-31
NCT02320539	MicroRNA Diagnostics in Subarachnoid Hemorrhage 2	https://ClinicalTrials.gov/show/NCT02320539	Completed	Rigshospitalet, Denmark	2015-05-31
NCT04387669	Maneuver for Evaluating the Potential Recruitability of the Pulmonary Parenchyme in Patients With ARDS	https://ClinicalTrials.gov/show/NCT04387669	Recruiting	University Hospital, Caen	2021-10-20
NCT04158479	China Extracorporeal Life Support Registry	https://ClinicalTrials.gov/show/NCT04158479	Recruiting	Beijing Anzhen Hospital	2025-12-31
NCT04068038	Pediatric Acute Respiratory Distress Syndrome Asia Study	https://ClinicalTrials.gov/show/NCT04068038	Recruiting	KK Women’s and Children’s Hospital	2022-08-01
NCT04031794	ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory Failure	https://ClinicalTrials.gov/show/NCT04031794	Recruiting	Mahidol University	2025-07-30
NCT03969407	Determination of the Best Positive End-expiratory Pressure (PEEP)	https://ClinicalTrials.gov/show/NCT03969407	Completed	Centre Chirurgical Marie Lannelongue	2019-06-20
NCT03513809	Inflammation and Distribution of Pulmonary Ventilation Before and After Tracheal Intubation in ARDS Patients	https://ClinicalTrials.gov/show/NCT03513809	Recruiting	Pontificia Universidad Catolica de Chile	2021-06-08
NCT03255109	WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE	https://ClinicalTrials.gov/show/NCT03255109	Completed	European Society of Intensive Care Medicine	2018-05-31
NCT04209270	Breathing Pattern, WOB and Gas Exchange in Patients With Acute Respiratory Distress Syndrome During the Spontaneous Breathing Trial	https://ClinicalTrials.gov/show/NCT04209270	Recruiting	Sanatorio de la Trinidad Mitre	2022-12-01