Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 411
interventional 249
Observational 148
Registry 14

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 53
Other 41
Drug|placebo 36
Procedure 33
Device 31
Biological 11
Device|Other 9
Drug|Other 5
Behavioral 4
Biological|Other 4
Biological|placebo 4
Device|Procedure 3
Drug|Procedure 3
Behavioral|Other 2
Other|Procedure 2
Behavioral|Radiation 1
Biological|Drug 1
Biological|Procedure 1
Device|Drug 1
Diagnostic Test 1
Dietary Supplement|placebo 1
Drug|Other|Procedure 1
Drug|Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 74
France 40
China 19
NA 13
Italy 12
United Kingdom 10
Spain 9
United States|Canada 7
Canada 5
Germany 5
Austria 4
Brazil 4
Taiwan 4
Egypt 3
Korea, Republic of 3
Mexico 3
Netherlands 3
Turkey 3
Greece 2
Iran, Islamic Republic of 2
Japan 2
Russian Federation 2
Sweden 2
Thailand 2
Argentina 1
Austria|France|United Kingdom 1
Belgium 1
Canada|France 1
Canada|Saudi Arabia 1
Denmark 1
France|Italy|Spain|Tunisia 1
Norway 1
Singapore 1
Switzerland 1
United States|Australia|Belgium|Canada|New Zealand|Spain 1
United States|Australia|Canada|Malaysia|Netherlands|Thailand 1
United States|Austria|Germany|Israel 1
United States|France|Spain|United Kingdom 1
United States|Israel 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 169
2 20
3 4
4 7
5 12
6 5
7 3
8 1
9 1
10 2
12 1
13 1
14 4
15 1
16 2
17 2
19 1
20 1
21 2
24 1
29 3
39 1
43 1
44 1
47 2
110 1

Phase

Phase Study_Count
N/A 120
Phase 2 44
Phase 3 32
Phase 1/Phase 2 17
Phase 1 15
Phase 4 14
Phase 2/Phase 3 5
Early Phase 1 2

Number of Arms

Number_of_Arms Count_of_Studies
1 43
2 156
3 23
4 4
5 2
7 1
NA 20

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 9.0 5.0000 3.00000 9.0000 10.0000 43 11.0000 10.0000
1st Qu. 10.5 30.0000 14.50000 26.0000 39.5000 60 122.0000 50.0000
Median 12.0 75.0000 20.00000 40.0000 69.5000 313 259.0000 85.0000
Mean 12.0 161.2017 39.53333 102.7647 110.3864 328 417.3448 174.2143
3rd Qu. 13.5 184.0000 50.50000 86.0000 135.0000 524 500.0000 188.2500
Max. 15.0 1250.0000 190.00000 600.0000 580.0000 700 1500.0000 651.0000

Trial Group Type

group_type Group_Count
Experimental 241
Active Comparator 100
Placebo Comparator 55
No Intervention 30
Other 26
NA 20
Sham Comparator 5

Intervention Model

intervention_model Study_Count
Parallel Assignment 166
Single Group Assignment 53
Crossover Assignment 13
Factorial Assignment 7
Sequential Assignment 5
NA 5

Primary Purpose

primary_purpose Study_Count
Treatment 186
Prevention 25
Diagnostic 15
Supportive Care 9
Other 7
Basic Science 3
Health Services Research 2
Screening 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
France 31
United States 27
China 14
Italy 11
NA 8
Taiwan 7
Spain 6
United Kingdom 6
Germany 4
India 3
Argentina 2
Belgium 2
Canada 2
Norway 2
Singapore 2
Sweden 2
Australia 1
Bangladesh|India|Iran, Islamic Republic of|Malaysia|Maldives|Nepal|Pakistan|Sri Lanka|Thailand|Vietnam 1
Belgium|France 1
Brazil 1
Brazil|Canada|Italy|Spain 1
Canada|China|France 1
Croatia 1
Cyprus|Finland|Netherlands 1
Egypt 1
Finland|France|Germany|Italy|Sweden|United Kingdom 1
France|Germany|Spain 1
Greece 1
Korea, Republic of 1
Lebanon 1
Malaysia 1
Sierra Leone 1
Turkey 1
United States|Austria|Belgium|Canada|France|Germany|Italy|Netherlands|Spain|Sweden|Switzerland|United Kingdom 1
United States|Estonia|Germany|Italy|Lithuania|Netherlands|Norway|Slovenia 1

Sites per Study

Site_count Study_Count
1 119
2 6
3 2
4 4
5 3
6 2
7 1
11 1
13 1
15 1
16 1
18 1
19 1
20 1
26 1
28 1
51 1
58 1

Enrollment Metrics

Measure Observational
Min 2.0000
1st Qu 35.0000
Median 100.0000
Mean 598.4236
3rd Qu 300.0000
Max 14000.0000

Observation Model

observational_model Study_Count
Cohort 96
Case-Only 15
Case-Control 12
NA 9
Case Control 7
Other 7
Defined Population, Natural History 1
Natural History 1

Time Perspective

time_perspective Study_Count
Prospective 119
Retrospective 14
Cross-Sectional 7
Other 3
NA 3
Cross-Sectional, Retrospective/Prospective 1
Longitudinal, Retrospective 1

Registries

Studies by Country

Country Study_Count
Argentina 2
China 2
France 2
Spain 2
Belgium 1
Canada 1
Chile 1
China|Hong Kong|India|Indonesia|Japan|Malaysia|Pakistan|Singapore|Thailand|Vietnam 1
Denmark 1
Thailand 1

Sites per Study

Site_count Study_Count
1 10
2 1
4 1
19 1
31 1

Enrollment Metrics

Measure Registries
Min 29.000
1st Qu 49.000
Median 225.000
Mean 1521.643
3rd Qu 950.000
Max 11000.000

Registry Model

observational_model Study_Count
Cohort 13
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 13
Other 1

Follow-up

target_duration Study_Count
60 Days 3
1 Year 2
28 Days 2
6 Months 2
1 Day 1
1 Month 1
2 Years 1
4 Days 1
90 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03376854 Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS https://ClinicalTrials.gov/show/NCT03376854 Recruiting University of Maryland, Baltimore 2020-11-30
NCT04371016 Pulmonary and Ventilatory Effects of Bed Verticalization in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04371016 Recruiting University Hospital, Clermont-Ferrand 2021-09-30
NCT04305457 Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19 https://ClinicalTrials.gov/show/NCT04305457 Active, not recruiting Massachusetts General Hospital 2021-04-01
NCT04235608 SEvoflurane for Sedation in ARds https://ClinicalTrials.gov/show/NCT04235608 Recruiting University Hospital, Clermont-Ferrand 2024-05-03
NCT04023305 Sevoflurane PharmacokInetics in ARDS https://ClinicalTrials.gov/show/NCT04023305 Recruiting University Hospital, Clermont-Ferrand 2022-03-01
NCT03372525 Invasive Ventilation Strategies for Neonates With Acute Respiratory Distress Syndrome Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03372525 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2020-12-31
NCT03371498 Procollagen-3 Driven Corticosteroids for Persistent Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03371498 Recruiting Assistance Publique Hopitaux De Marseille 2020-06-15
NCT04397510 Nebulized Heparin for the Treatment of COVID-19 Induced Lung Injury https://ClinicalTrials.gov/show/NCT04397510 Enrolling by invitation Frederick Health 2020-12-31
NCT04308668 Post-exposure Prophylaxis / Preemptive Therapy for SARS-Coronavirus-2 https://ClinicalTrials.gov/show/NCT04308668 Completed University of Minnesota 2020-05-20
NCT03368092 Inhaled Dornase Alpha to Reduce Respiratory Failure After Severe Trauma https://ClinicalTrials.gov/show/NCT03368092 Recruiting University Hospital, Strasbourg, France 2021-10-01
NCT03589482 Assessing Lung Inhomogeneity During Ventilation for Acute Hypoxemic Respiratory Failure https://ClinicalTrials.gov/show/NCT03589482 Recruiting University Health Network, Toronto 2019-12-31
NCT03337373 The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium https://ClinicalTrials.gov/show/NCT03337373 Completed Mahidol University 2018-08-31
NCT03328117 A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury https://ClinicalTrials.gov/show/NCT03328117 Completed Exvastat Ltd. 2018-03-05
NCT03303807 Correction by ECCO2-R of Hypercapnia in Patients With DVP in Moderate to Severe ARDS Under Protective Ventilation. https://ClinicalTrials.gov/show/NCT03303807 Completed Assistance Publique - Hôpitaux de Paris 2019-02-25
NCT03296059 Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates https://ClinicalTrials.gov/show/NCT03296059 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2021-10-01
NCT03281473 Comparison of Positive End Expiratory Pressure Titration Methods in ARDS Patients https://ClinicalTrials.gov/show/NCT03281473 Recruiting University Hospital, Angers 2019-12-31
NCT03217162 Surfactant for Neonate With Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03217162 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2021-07-30
NCT03217149 Heliox for Neonate With Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03217149 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2020-08-30
NCT03202641 Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients https://ClinicalTrials.gov/show/NCT03202641 Recruiting Massachusetts General Hospital 2020-04-01
NCT03202394 Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS https://ClinicalTrials.gov/show/NCT03202394 Completed BioMarck Pharmaceuticals, Ltd. 2020-03-30
NCT03111212 Iloprost in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03111212 Recruiting University Hospital Tuebingen 2021-10-31
NCT03096314 Vitamin D to Improve Outcomes by Leveraging Early Treatment https://ClinicalTrials.gov/show/NCT03096314 Completed Massachusetts General Hospital 2018-12-11
NCT03089957 Prevention of Ulinastatin on Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03089957 Recruiting Peking University Third Hospital 2019-12-31
NCT03085615 Feeding the Critically Ill During Phases of Altered Redox Status https://ClinicalTrials.gov/show/NCT03085615 Completed University of Illinois at Chicago 2018-06-04
NCT03042143 Repair of Acute Respiratory Distress Syndrome by Stromal Cell Administration (REALIST) (COVID-19) https://ClinicalTrials.gov/show/NCT03042143 Recruiting Belfast Health and Social Care Trust 2020-09-30
NCT03031275 Long-term Follow Up of Adult Patients Treated With Extracorporeal Membrane Oxygenation for Respiratory Failure https://ClinicalTrials.gov/show/NCT03031275 Completed Karolinska University Hospital 2016-12-31
NCT03023670 Lung Protection and Pediatric Cardiac Surgery https://ClinicalTrials.gov/show/NCT03023670 Completed Assiut University 2018-03-31
NCT02978885 Imaging of Peri-operative (periOP) Lung Injury https://ClinicalTrials.gov/show/NCT02978885 Recruiting Columbia University 2020-09-30
NCT02963558 A Study Promoting Critical Illness Recovery in the Elderly https://ClinicalTrials.gov/show/NCT02963558 Active, not recruiting Wake Forest University Health Sciences 2021-06-30
NCT02895373 PGE1 as Additive Anticoagulant in ECMO-Therapy https://ClinicalTrials.gov/show/NCT02895373 Recruiting Medical University of Vienna 2019-07-31
NCT02892799 Non-invasive Fluid Management https://ClinicalTrials.gov/show/NCT02892799 Recruiting Intermountain Health Care, Inc. 2020-12-31
NCT02891837 L-citrulline for Prevention of Sequelae of Acute Lung Injury in Pediatrics Undergoing Cardiopulmonary Bypass for Heart Defects https://ClinicalTrials.gov/show/NCT02891837 Completed Asklepion Pharmaceuticals, LLC 2019-06-30
NCT02859194 The Effect of Lt to Rt Shunt Using Veno-veno-arterial Extracorporeal Membrane Oxygenation (ECMO) on Coronary Oxygenation in Lung Transplantation Patients https://ClinicalTrials.gov/show/NCT02859194 Completed Yonsei University 2016-10-14
NCT02819453 Corticosteroid Mediates Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02819453 Completed Shanghai Pulmonary Hospital, Shanghai, China 2017-07-31
NCT02816372 Ultra Protective Ventilation Without Extracorporeal Circulation in Severe ARDS Patients (VT4ARDS) https://ClinicalTrials.gov/show/NCT02816372 Completed Hospices Civils de Lyon 2018-06-14
NCT02816359 Position and Esophageal Pressure https://ClinicalTrials.gov/show/NCT02816359 Completed Hospices Civils de Lyon 2017-09-30
NCT02814994 Respiratory System Compliance Guided VT in Moderate to Severe ARDS Patients https://ClinicalTrials.gov/show/NCT02814994 Completed Southeast University, China 2014-05-31
NCT02804945 Mesenchymal Stem Cells (MSCs) for Treatment of Acute Respiratory Distress Syndrome (ARD) in Patients With Malignancies https://ClinicalTrials.gov/show/NCT02804945 Completed M.D. Anderson Cancer Center 2019-06-13
NCT02787720 Rehabilitation Techniques on Survivors of Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02787720 Completed Baqiyatallah Medical Sciences University 2014-10-31
NCT02734654 Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage https://ClinicalTrials.gov/show/NCT02734654 Completed Instituto de Salud Carlos III 2011-02-28
NCT02713451 Liberal Oxygenation Versus Conservative Oxygenation in ARDS https://ClinicalTrials.gov/show/NCT02713451 Active, not recruiting Centre Hospitalier Universitaire de Besancon 2019-05-31
NCT02611609 A Phase 1/2 Study to Assess MultiStem® Therapy in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02611609 Completed Athersys, Inc 2018-09-30
NCT02574169 Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation https://ClinicalTrials.gov/show/NCT02574169 Recruiting University Hospital, Toulouse 2019-03-31
NCT04370834 Tocilizumab for Patients With Cancer and COVID-19 Disease https://ClinicalTrials.gov/show/NCT04370834 Recruiting National Cancer Institute (NCI) 2021-11-01
NCT04327401 COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III https://ClinicalTrials.gov/show/NCT04327401 Active, not recruiting Hospital Sirio-Libanes 2020-08-30
NCT02546947 Monitoring in Intensive Care Unit of Neuromuscular Blocking Agents Used for Acute Respiratory Distress Syndrome After Cardiothoracic Surgery https://ClinicalTrials.gov/show/NCT02546947 Completed Centre Chirurgical Marie Lannelongue 2016-12-31
NCT02509078 Reevaluation Of Systemic Early Neuromuscular Blockade https://ClinicalTrials.gov/show/NCT02509078 Completed Massachusetts General Hospital 2018-07-03
NCT02468908 Inhaled Molgramostim (rhGM-CSF) in Healthy Adult Subjects https://ClinicalTrials.gov/show/NCT02468908 Completed Savara Inc. 2015-10-31
NCT02463773 Diaphragm Ultrasound Vs Transpulmonary Pressure To Set PEEP in ARDS https://ClinicalTrials.gov/show/NCT02463773 Completed University of Minnesota 2016-07-31
NCT02450825 Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration https://ClinicalTrials.gov/show/NCT02450825 Completed Centre hospitalier de l’Université de Montréal (CHUM) 2017-02-28
NCT02425579 Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT02425579 Completed Brigham and Women’s Hospital 2019-08-31
NCT02416037 Trans-pulmonary Pressure in ARDS https://ClinicalTrials.gov/show/NCT02416037 Completed Hospices Civils de Lyon 2017-04-13
NCT02403791 Point-of-Care Bedside Lung Ultrasound Examination Advanced Trial Protocol https://ClinicalTrials.gov/show/NCT02403791 Completed Nanjing Medical University 2015-03-31
NCT02282657 Strategy of UltraProtective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to seVere ARDS https://ClinicalTrials.gov/show/NCT02282657 Completed European Society of Intensive Care Medicine 2017-07-31
NCT02273687 Time-motion-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in Emergency Department https://ClinicalTrials.gov/show/NCT02273687 Completed Centre Hospitalier Universitaire de Nīmes 2017-09-29
NCT02252094 Ultra-protective Pulmonary Ventilation Supported by Low Flow ECCO2R for Severe ARDS https://ClinicalTrials.gov/show/NCT02252094 Recruiting National University Health System, Singapore 2019-12-31
NCT02027181 Automatic Administration of Oxygen During Respiratory Distress https://ClinicalTrials.gov/show/NCT02027181 Completed University Hospital, Brest 2014-10-31
NCT02166853 Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study) https://ClinicalTrials.gov/show/NCT02166853 Completed University Hospital, Clermont-Ferrand 2016-02-29
NCT02027129 Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO https://ClinicalTrials.gov/show/NCT02027129 Completed University of Athens 2016-10-31
NCT02106975 Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury https://ClinicalTrials.gov/show/NCT02106975 Completed Virginia Commonwealth University 2017-11-16
NCT02097641 Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START) https://ClinicalTrials.gov/show/NCT02097641 Completed University of California, San Francisco 2017-03-09
NCT02064140 Supported Ventilation in ARDS Patients https://ClinicalTrials.gov/show/NCT02064140 Completed University Medical Center Nijmegen 2014-11-30
NCT02058004 Does Cricoid Pressure Reduce the Risk of Aspiration? https://ClinicalTrials.gov/show/NCT02058004 Completed Mayo Clinic 2014-10-31
NCT01289600 Mechanical Ventilation and Respiratory Muscle Work of Breathing in Acute Respiratory Distress Syndrome (ARDS) Patients https://ClinicalTrials.gov/show/NCT01289600 Completed University Medical Center Nijmegen 2013-03-31
NCT01284452 Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01284452 Completed Mahidol University 2014-12-31
NCT01274481 Iloprost Effects on Gas Exchange and Pulmonary Mechanics https://ClinicalTrials.gov/show/NCT01274481 Completed University of Oklahoma 2012-07-31
NCT01272882 Electrical Impedance Tomography (EIT) Monitoring in Adults With ALI or ARDS https://ClinicalTrials.gov/show/NCT01272882 Completed Christiana Care Health Services 2011-03-31
NCT04442958 Effectiveness of Convalescent Immune Plasma Therapy https://ClinicalTrials.gov/show/NCT04442958 Completed Bagcilar Training and Research Hospital 2020-06-15
NCT04369469 Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia https://ClinicalTrials.gov/show/NCT04369469 Recruiting Alexion Pharmaceuticals 2020-11-30
NCT04312009 Losartan for Patients With COVID-19 Requiring Hospitalization https://ClinicalTrials.gov/show/NCT04312009 Recruiting University of Minnesota 2021-04-01
NCT02439151 New Lung Ventilation Strategies Guided by Transpulmonary Pressure in VV-ECMO for Severe ARDS https://ClinicalTrials.gov/show/NCT02439151 Completed Beijing Chao Yang Hospital 2020-06-25
NCT01899560 ELASTANCE: Prospective Physiological Study of Lung Elastance in Recruitment and Derecruitment in Early Onset Mechanically Ventilated ARDS Patients https://ClinicalTrials.gov/show/NCT01899560 Completed Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer 2013-06-30
NCT01883869 Targeting Platelet-Leukocyte Aggregates in Pneumonia With Ticagrelor https://ClinicalTrials.gov/show/NCT01883869 Completed University of Kentucky 2016-06-30
NCT01783821 LIPS-B: Lung Injury Prevention Study With Budesonide and Beta https://ClinicalTrials.gov/show/NCT01783821 Completed Mayo Clinic 2015-07-31
NCT01768949 Echocardiography Predictive of the Inefficacy and/or of the Unsafeness of Recruitment Maneuvers in Patients With Acute Respiratory Distress Syndrome. https://ClinicalTrials.gov/show/NCT01768949 Completed Centre Hospitalier Universitaire de Besancon 2017-01-31
NCT01743105 Reproductibility of TM-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in the ER https://ClinicalTrials.gov/show/NCT01743105 Completed Centre Hospitalier Universitaire de Nīmes 2014-01-31
NCT01731795 Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01731795 Completed Dr. Negrin University Hospital 2019-02-12
NCT04153487 Role of Ascorbic Acid Infusion in Critically Ill Patients With Transfusion Related Acute Lung Injury https://ClinicalTrials.gov/show/NCT04153487 Recruiting Damanhour University 2020-12-31
NCT01683669 Effect of Variable PSV in Acute Lung Injury: Part I and Part II https://ClinicalTrials.gov/show/NCT01683669 Completed University of Genova 2016-12-31
NCT01680783 Non-Invasive Ventilation Via a Helmet Device for Patients Respiratory Failure https://ClinicalTrials.gov/show/NCT01680783 Completed University of Chicago 2016-05-31
NCT01659307 The Effect of Aspirin on REducing iNflammation in Human in Vivo Model of Acute Lung Injury https://ClinicalTrials.gov/show/NCT01659307 Recruiting Belfast Health and Social Care Trust 2019-08-31
NCT01640990 A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers https://ClinicalTrials.gov/show/NCT01640990 Completed GlaxoSmithKline 2011-12-09
NCT01627613 Study in Intensive Care Patients to Investigate the Clinical Effect of Repetitive Orally Inhaled Doses of AP301 on Alveolar Liquid Clearance in Acute Lung Injury https://ClinicalTrials.gov/show/NCT01627613 Completed Apeptico Forschung und Entwicklung GmbH 2014-05-31
NCT01600651 Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) https://ClinicalTrials.gov/show/NCT01600651 Completed University Hospital, Clermont-Ferrand 2013-10-31
NCT01597635 The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury https://ClinicalTrials.gov/show/NCT01597635 Completed GlaxoSmithKline 2014-10-01
NCT01585922 Noninvasive Positive Pressure Ventilation in Moderate Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01585922 Completed Beijing Hospital 2016-12-31
NCT01581229 Early Use of Noninvasive Positive Pressure Ventilation for Intro-pulmonary Acute Lung Injury https://ClinicalTrials.gov/show/NCT01581229 Completed Beijing Hospital 2016-12-31
NCT01552070 Recruitment on Extravascular Lung Water in Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01552070 Completed Chang Gung Memorial Hospital 2013-05-31
NCT01532024 Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs https://ClinicalTrials.gov/show/NCT01532024 Completed University of Edinburgh 2016-09-02
NCT01526382 Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01526382 Completed Jinhua Central Hospital 2014-06-30
NCT01519258 Mechanical Ventilation With Neurally-Adjusted Ventilatory Assist in Patients With ARDS https://ClinicalTrials.gov/show/NCT01519258 Completed University of Sao Paulo General Hospital 2015-11-30
NCT01504893 Protective Ventilation With Low Tidal Volume Versus an Ultraprotective Ventilatory Strategy for One-lung Ventilation in Patients Undergoing Thoracic Anesthesia. https://ClinicalTrials.gov/show/NCT01504893 Completed Azienda Ospedaliera S. Maria della Misericordia 2016-08-31
NCT01504867 LIPS-A: Lung Injury Prevention Study With Aspirin https://ClinicalTrials.gov/show/NCT01504867 Completed Mayo Clinic 2015-09-30
NCT01502332 Intensive Alveolar Recruitment Protocol After Cardiac Surgery https://ClinicalTrials.gov/show/NCT01502332 Completed University of Sao Paulo 2014-02-28
NCT01474863 Citrulline in Severe Sepsis https://ClinicalTrials.gov/show/NCT01474863 Completed Vanderbilt University Medical Center 2016-03-31
NCT01470703 Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01470703 Completed Assistance Publique - Hôpitaux de Paris 2017-07-31
NCT01438853 Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01438853 Completed Altor BioScience 2006-07-31
NCT01434121 Ascorbic Acid (Vitamin C) Infusion in Human Sepsis https://ClinicalTrials.gov/show/NCT01434121 Completed Virginia Commonwealth University 2012-09-30
NCT01423864 Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01423864 Completed National Taiwan University Hospital 2009-06-30
NCT01373905 Stepwise Positive End Expiratory Pressure Elevation For Lung Recruitment in Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01373905 Completed University of Alexandria 2008-02-29
NCT01335932 Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure https://ClinicalTrials.gov/show/NCT01335932 Completed Fred Hutchinson Cancer Research Center 2016-06-17
NCT01320384 Clinical Effect of the Association of Noninvasive Ventilation and High Flow Nasal Oxygen Therapy in Resuscitation of Patients With Acute Lung Injury (FLORALI Study) https://ClinicalTrials.gov/show/NCT01320384 Completed Poitiers University Hospital 2013-07-31
NCT04447833 Mesenchymal Stromal Cell Therapy For The Treatment Of Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04447833 Recruiting Uppsala University 2020-12-30
NCT04435535 Chest Physiotherapy in Tracheotomized Patients https://ClinicalTrials.gov/show/NCT04435535 Completed Linkoeping University 2017-03-31
NCT04434001 ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery https://ClinicalTrials.gov/show/NCT04434001 Recruiting IRCCS Policlinico S. Donato 2020-08-10
NCT04416139 Mesenchymal Stem Cell for Acute Respiratory Distress Syndrome Due for COVID-19 https://ClinicalTrials.gov/show/NCT04416139 Recruiting Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran 2021-04-30
NCT04412057 Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury https://ClinicalTrials.gov/show/NCT04412057 Recruiting Cerecor Inc 2020-10-31
NCT04402866 TD-0903 for ALI Associated With COVID-19 https://ClinicalTrials.gov/show/NCT04402866 Recruiting Theravance Biopharma 2020-10-31
NCT04402840 Stellate Ganglion Block (SGB) for COVID-19 Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT04402840 Recruiting West Virginia University 2020-07-31
NCT04402060 A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 https://ClinicalTrials.gov/show/NCT04402060 Recruiting Apellis Pharmaceuticals, Inc. 2020-11-30
NCT04395105 Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial https://ClinicalTrials.gov/show/NCT04395105 Recruiting Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno 2020-12-31
NCT04391140 Prone Positioning and High-flow Nasal Cannula in COVID-19 Induced ARDS https://ClinicalTrials.gov/show/NCT04391140 Recruiting Hospital Universitari Vall d’Hebron Research Institute 2020-12-31
NCT04390139 Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 https://ClinicalTrials.gov/show/NCT04390139 Recruiting Banc de Sang i Teixits 2020-10-31
NCT04389840 Dociparstat for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure https://ClinicalTrials.gov/show/NCT04389840 Recruiting Chimerix 2021-02-28
NCT04388826 COVID-19 Treatment of Severe Acute Respiratory Syndrome With Veru-111 https://ClinicalTrials.gov/show/NCT04388826 Recruiting Veru Inc. 2020-07-30
NCT04382391 Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms https://ClinicalTrials.gov/show/NCT04382391 Recruiting Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) 2020-09-01
NCT04378920 A Study of Trans Crocetin in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Disease (LEAF-4L7520/4L6715) https://ClinicalTrials.gov/show/NCT04378920 Recruiting Institut de Cancerologie Strasbourg Europe 2020-07-31
NCT04373200 Human Ab Response & immunoMONItoring of COVID-19 Patients https://ClinicalTrials.gov/show/NCT04373200 Recruiting Rennes University Hospital 2020-11-25
NCT04371393 MSCs in COVID-19 ARDS https://ClinicalTrials.gov/show/NCT04371393 Recruiting Icahn School of Medicine at Mount Sinai 2021-04-30
NCT04369599 Trans Thoracic Manipulation of Ventilation/Perfusion: the V/Q Vest for COVID-19 https://ClinicalTrials.gov/show/NCT04369599 Enrolling by invitation Emory University 2021-03-31
NCT04366063 Mesenchymal Stem Cell Therapy for SARS-CoV-2-related Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04366063 Recruiting Royan Institute 2020-06-06
NCT04361526 Pilot Study on Cytokine Filtration in COVID-19 ARDS https://ClinicalTrials.gov/show/NCT04361526 Recruiting Hospital Clinic of Barcelona 2020-07-31
NCT04359862 Sedation With Sevoflurane Versus Propofol in Patients With Acute Respiratory Distress Syndrome Caused by COVID19 Infection https://ClinicalTrials.gov/show/NCT04359862 Recruiting Fundación para la Investigación del Hospital Clínico de Valencia 2020-08-16
NCT04359251 Different PEEP Settings of COVID-19 Induced ARDS https://ClinicalTrials.gov/show/NCT04359251 Completed Southeast University, China 2020-03-25
NCT04357730 Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection https://ClinicalTrials.gov/show/NCT04357730 Recruiting Denver Health and Hospital Authority 2020-09-30
NCT04355728 Use of UC-MSCs for COVID-19 Patients https://ClinicalTrials.gov/show/NCT04355728 Recruiting University of Miami 2021-04-30
NCT04355364 Efficacy and Safety of Aerosolized Intra-tracheal Dornase Alfa Administration in Patients With COVID19-induced ARDS (COVIDORNASE) https://ClinicalTrials.gov/show/NCT04355364 Recruiting Fondation Ophtalmologique Adolphe de Rothschild 2020-08-21
NCT04352725 Effect of PEEP Titration on the EELV Measured by the Nitrogen Dilution Technique in ARDS https://ClinicalTrials.gov/show/NCT04352725 Recruiting Centre Hospitalier Intercommunal Aix-Pertuis 2020-11-30
NCT04351906 Low-flow Extracorporeal Carbon Dioxide Removal in COVID-19-associated Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04351906 Recruiting University of Giessen 2020-07-31
NCT04350736 First in Human SAD and MAD Study of Inhaled TD-0903, a Potential Treatment for ALI Associated With COVID-19 https://ClinicalTrials.gov/show/NCT04350736 Recruiting Theravance Biopharma 2020-06-30
NCT04350580 Polyvalent Immunoglobulin in COVID-19 Related ARds https://ClinicalTrials.gov/show/NCT04350580 Recruiting Centre Hospitalier St Anne 2020-06-30
NCT04347980 Dexamethasone Treatment for Severe Acute Respiratory Distress Syndrome Induced by COVID-19 https://ClinicalTrials.gov/show/NCT04347980 Recruiting Centre Chirurgical Marie Lannelongue 2020-06-30
NCT04335786 Valsartan for Prevention of Acute Respiratory Distress Syndrome in Hospitalized Patients With SARS-COV-2 (COVID-19) Infection Disease https://ClinicalTrials.gov/show/NCT04335786 Recruiting Radboud University 2020-12-31
NCT04333368 Cell Therapy Using Umbilical Cord-derived Mesenchymal Stromal Cells in SARS-CoV-2-related ARDS https://ClinicalTrials.gov/show/NCT04333368 Recruiting Assistance Publique - Hôpitaux de Paris 2020-08-31
NCT04331613 Safety and Efficacy of CAStem for Severe COVID-19 Associated With/Without ARDS https://ClinicalTrials.gov/show/NCT04331613 Recruiting Chinese Academy of Sciences 2020-12-31
NCT04328467 Pre-exposure Prophylaxis for SARS-Coronavirus-2 https://ClinicalTrials.gov/show/NCT04328467 Active, not recruiting University of Minnesota 2020-08-31
NCT04325685 The Effect of Supraglottic and Oropharyngeal Decontamination on the Incidence of Ventilator-associated Pneumonia https://ClinicalTrials.gov/show/NCT04325685 Active, not recruiting Northern State Medical University 2021-12-31
NCT04325061 Efficacy of Dexamethasone Treatment for Patients With ARDS Caused by COVID-19 https://ClinicalTrials.gov/show/NCT04325061 Recruiting Dr. Negrin University Hospital 2020-10-30
NCT04321616 The Efficacy of Different Anti-viral Drugs in COVID 19 Infected Patients https://ClinicalTrials.gov/show/NCT04321616 Recruiting Oslo University Hospital 2020-08-31
NCT04289324 Open Lung Maneuvers During High Frequency Oscillatory Ventilation in Preterm Infants https://ClinicalTrials.gov/show/NCT04289324 Recruiting Medical University of Vienna 2022-06-30
NCT04289194 Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04289194 Active, not recruiting Histocell, S.L. 2021-07-31
NCT04133740 Oxygenation Targets in Cardiac Surgery Patients - a Before-and-after Study https://ClinicalTrials.gov/show/NCT04133740 Active, not recruiting Aalborg University Hospital 2019-07-15
NCT04115709 Decision Support System to Evaluate VENTilation in ARDS https://ClinicalTrials.gov/show/NCT04115709 Recruiting Imperial College London 2021-03-30
NCT04106128 Prevalence, Impact and Reversibility of Acute Diaprhagmatic Dysfunction in Acute Respiratory Detresse https://ClinicalTrials.gov/show/NCT04106128 Recruiting Centre Hospitalier Universitaire de Nice 2020-10-05
NCT04070053 Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway https://ClinicalTrials.gov/show/NCT04070053 Recruiting University of Calgary 2021-01-31
NCT04028336 The Strategy of “Pulmonary Opening by Titration of Positive End-expiratory Pressure” Means of a Pulmonary Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome: for Which Patients? https://ClinicalTrials.gov/show/NCT04028336 Recruiting Centre Hospitalier de Lens 2021-01-07
NCT04014218 Effect of Inhalation Sedation Compared With Propofol on the Sepsis-related Acute Respiratory Distress Syndrome Course https://ClinicalTrials.gov/show/NCT04014218 Recruiting Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy 2019-09-30
NCT03984175 Clinical Decision Support for Mechanical Ventilation of Patients With ARDS https://ClinicalTrials.gov/show/NCT03984175 Recruiting Intermountain Health Care, Inc. 2020-09-01
NCT03926533 Telehealth-Enhanced Patient-Oriented Recovery Trajectory After ICU https://ClinicalTrials.gov/show/NCT03926533 Recruiting Vanderbilt University 2021-06-30
NCT03909854 Pragmatic Investigation of Volume Targeted Ventilation-1 https://ClinicalTrials.gov/show/NCT03909854 Active, not recruiting Wake Forest University Health Sciences 2019-11-12
NCT03905837 Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery https://ClinicalTrials.gov/show/NCT03905837 Recruiting Hospital General Universitario Gregorio Marañon 2021-05-28
NCT03896802 Hemodynamic Effects of PEEP in ARDS https://ClinicalTrials.gov/show/NCT03896802 Recruiting University of Milan 2019-12-31
NCT03818854 Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03818854 Recruiting University of California, San Francisco 2023-07-01
NCT03807804 Efficacy and Safety Study of HLCM051(MultiStem®) for Pneumonic Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03807804 Recruiting Healios K.K. 2020-12-31
NCT03799874 Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03799874 Active, not recruiting Brigham and Women’s Hospital 2022-12-31
NCT03793842 Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03793842 Recruiting University of Michigan 2021-01-31
NCT03764319 Low Frequency, Ultra-low Tidal Volume Ventilation in Patients With ARDS and VV-ECMO https://ClinicalTrials.gov/show/NCT03764319 Recruiting Medical University of Vienna 2020-05-06
NCT03753022 Effects of PEEP on Parameters of Tissue Perfusion in Patients Post Cardiac Surgery https://ClinicalTrials.gov/show/NCT03753022 Active, not recruiting Federal University of São Paulo 2019-12-31
NCT03736707 Selective High Frequency Oscillatory Ventilation (HFOV) for Neonates https://ClinicalTrials.gov/show/NCT03736707 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2022-12-12
NCT03719937 Artificial Increase in Chest Wall Elastance as an Alternative to Prone Positioning in Moderate-to-severe ARDS. https://ClinicalTrials.gov/show/NCT03719937 Recruiting Catholic University of the Sacred Heart 2021-04-01
NCT03712215 STUDY OF ELECTRICAL STIMULATION IN PULMONARY FUNCTION IN INTENSIVE CARE UNIT https://ClinicalTrials.gov/show/NCT03712215 Recruiting Universidade Metodista de Piracicaba 2019-01-31
NCT03651817 Lung Protection Strategy in Open Heart Surgery: Which Tidal Volume is Better 8ml/kg or 6ml/kg https://ClinicalTrials.gov/show/NCT03651817 Completed Kocaeli University 2019-11-20
NCT03642002 The Effects of Music Therapy on Adult Patients Requiring Mechanical Ventilation in the ICU https://ClinicalTrials.gov/show/NCT03642002 Recruiting Icahn School of Medicine at Mount Sinai 2021-09-30
NCT03637530 a Study Conducted About a New Mode of Ventilation in Laparoscopic Surgeries https://ClinicalTrials.gov/show/NCT03637530 Active, not recruiting All India Institute of Medical Sciences, Rishikesh 2018-05-31
NCT03621293 Long Term Outcome on Brain and Lung of Different Oxygen Strategies in ARDS Patients https://ClinicalTrials.gov/show/NCT03621293 Recruiting Centre Hospitalier Universitaire de Besancon 2021-03-20
NCT03608592 Human Umbilical Cord Mesenchymal Stem Cells (MSCs) Therapy in ARDS https://ClinicalTrials.gov/show/NCT03608592 Recruiting Sun Yat-sen University 2020-08-01
NCT03552601 The Effect of Negatively Fluid Balancing Speed for ICU Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03552601 Recruiting Qingdao University 2020-12-01
NCT04456361 Use of Mesenchymal Stem Cells in Acute Respiratory Distress Syndrome Caused by COVID-19 https://ClinicalTrials.gov/show/NCT04456361 Active, not recruiting Instituto de Medicina Regenerativa 2020-07-15
NCT03498807 A Comparison of Optimal PEEP Determination Guided by EIT and Conventional Protective Ventilation Tool in ARDS Patients https://ClinicalTrials.gov/show/NCT03498807 Completed Far Eastern Memorial Hospital 2019-02-28
NCT03465085 Streptokinase Versus Unfractionated Heparin Nebulization in Severe ARDS https://ClinicalTrials.gov/show/NCT03465085 Completed Beni-Suef University 2018-01-30
NCT01260259 Seattle Cardiorenal Remote Ischemic Preconditioning Trial https://ClinicalTrials.gov/show/NCT01260259 Completed Seattle Children’s Hospital 2013-08-31
NCT01239966 Pulmonary And Renal Support During Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01239966 Completed Hôpital Européen Marseille 2014-12-31
NCT01194895 A Trial to Evaluate the Impact of Lung-protective Intervention in Patients Undergoing Esophageal Cancer Surgery https://ClinicalTrials.gov/show/NCT01194895 Completed Shanghai Zhongshan Hospital 2013-01-31
NCT01150864 Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial https://ClinicalTrials.gov/show/NCT01150864 Completed Università degli Studi dell’Insubria 2015-03-31
NCT01144585 Effects of Remote Ischemic Preconditioning and Postconditioning on Lung Injury During Cardiopulmonary Bypass https://ClinicalTrials.gov/show/NCT01144585 Completed Seoul National University Hospital 2010-11-30
NCT01119872 Pilot Study of Positive-End Expiratory Pressure in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01119872 Completed Hospital Universitario Principe de Asturias 2007-12-31
NCT01114009 Effects of Recruitment Maneuvers in Early Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) Patients https://ClinicalTrials.gov/show/NCT01114009 Completed Chi Mei Medical Hospital 2011-12-31
NCT01050699 Sleep Intervention During Acute Lung Injury https://ClinicalTrials.gov/show/NCT01050699 Active, not recruiting University of Arizona 2019-03-31
NCT00999713 CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients https://ClinicalTrials.gov/show/NCT00999713 Completed Milton S. Hershey Medical Center 2015-09-30
NCT00996840 SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS https://ClinicalTrials.gov/show/NCT00996840 Completed GlaxoSmithKline 2013-02-09
NCT00963066 NAV-ALI: Neurally Adjusted Ventilatory Assist in Patients Recovering Spontaneous Breathing After Acute Lung Injury https://ClinicalTrials.gov/show/NCT00963066 Completed University Hospital, Caen 2009-11-30
NCT00958685 Safety Study of Feeding With Ginger Extract in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00958685 Completed Shahid Beheshti University 2009-01-31
NCT00883948 Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) https://ClinicalTrials.gov/show/NCT00883948 Completed National Heart, Lung, and Blood Institute (NHLBI) 2011-03-31
NCT00879606 Anti-TF Antibody (ALT-836) to Treat Septic Patients With Acute Lung Injury or Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00879606 Completed Altor BioScience 2012-10-31
NCT03870009 Validation of a Semi-automatized Method to Detect Cyclic Hyperinflation on CT-scan in ARDS https://ClinicalTrials.gov/show/NCT03870009 Recruiting Hospices Civils de Lyon 2021-08-31
NCT00852605 Acute Lung Injury After Allogeneic Transplantation - Diagnosis and Early Treatment https://ClinicalTrials.gov/show/NCT00852605 Completed Technische Universität Dresden 2005-08-31
NCT04325906 Early PP With HFNC Versus HFNC in COVID-19 Induced Moderate to Severe ARDS https://ClinicalTrials.gov/show/NCT04325906 Recruiting Rush University Medical Center 2020-08-31
NCT04311177 Losartan for Patients With COVID-19 Not Requiring Hospitalization https://ClinicalTrials.gov/show/NCT04311177 Recruiting University of Minnesota 2021-04-01
NCT03591796 Invasive Ventilation for Neonates With Acute Respiratory Distress Syndrome(ARDS) https://ClinicalTrials.gov/show/NCT03591796 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2022-10-01
NCT00830284 Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury https://ClinicalTrials.gov/show/NCT00830284 Completed Boston Children’s Hospital 2012-12-31
NCT04402879 CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals https://ClinicalTrials.gov/show/NCT04402879 Recruiting University of Calgary 2020-12-01
NCT04358939 Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19) https://ClinicalTrials.gov/show/NCT04358939 Recruiting University Hospital, Tours 2020-11-10
NCT01775774 Human Mesenchymal Stem Cells For Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01775774 Completed University of California, San Francisco 2014-02-28
NCT01681225 EPVent 2- A Phase II Study of Mechanical Ventilation Directed by Transpulmonary Pressures https://ClinicalTrials.gov/show/NCT01681225 Completed Beth Israel Deaconess Medical Center 2017-10-12
NCT04139733 Early Use of Prone Position in ECMO for Severe ARDS https://ClinicalTrials.gov/show/NCT04139733 Recruiting Beijing Chao Yang Hospital 2022-08-31
NCT03462849 Expiratory Flow Limitation Assessment https://ClinicalTrials.gov/show/NCT03462849 Completed Hospices Civils de Lyon 2019-05-02
NCT04365985 Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 https://ClinicalTrials.gov/show/NCT04365985 Recruiting William Beaumont Hospitals 2021-05-31
NCT04351243 A Study to Assess the Efficacy and Safety of Gimsilumab in Subjects With Lung Injury or Acute Respiratory Distress Syndrome Secondary to COVID-19 (BREATHE). https://ClinicalTrials.gov/show/NCT04351243 Recruiting Kinevant Sciences GmbH 2020-10-31
NCT04311697 Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure https://ClinicalTrials.gov/show/NCT04311697 Recruiting NeuroRx, Inc. 2020-08-31
NCT03896763 PROSpect: Prone and Oscillation Pediatric Clinical Trial https://ClinicalTrials.gov/show/NCT03896763 Recruiting University of Pennsylvania 2023-05-31
NCT04221737 Early Use of Airway Pressure Release Ventilation (APRV) in ARDS https://ClinicalTrials.gov/show/NCT04221737 Recruiting Hospital Civil de Guadalajara 2025-11-30
NCT01862016 Early Spontaneous Breathing in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01862016 Active, not recruiting University Hospital, Angers 2017-12-16
NCT00789685 Safety, Tolerability and Preliminary Efficacy of FP-1201 in ALI and ARDS. Phase I/II https://ClinicalTrials.gov/show/NCT00789685 Completed Faron Pharmaceuticals Ltd 2011-09-30
NCT00786292 Evaluation of Variable Pressure Support Ventilation in the Therapy of Acute Lung Injury https://ClinicalTrials.gov/show/NCT00786292 Completed Technische Universität Dresden 2012-09-30
NCT00747045 Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients https://ClinicalTrials.gov/show/NCT00747045 Completed University of California, San Diego 2011-03-31
NCT00655928 Modulation of Lung Injury Complicating Lung Resection https://ClinicalTrials.gov/show/NCT00655928 Completed Imperial College London 2009-07-31
NCT00646152 Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study https://ClinicalTrials.gov/show/NCT00646152 Completed National Institutes of Health Clinical Center (CC) 2009-12-16
NCT00644930 Non-Invasive Positive Pressure Ventilation and Adult Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT00644930 Completed Eskisehir Osmangazi University 2005-09-30
NCT00624650 Hemodynamics and Extravascular Lung Water in Acute Lung Injury https://ClinicalTrials.gov/show/NCT00624650 Completed Oregon Health and Science University 2011-01-31
NCT00605696 Early Insulin and Development of ARDS https://ClinicalTrials.gov/show/NCT00605696 Completed Albert Einstein College of Medicine 2011-12-31
NCT00568659 The Specific Lung Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Supine and Prone Position https://ClinicalTrials.gov/show/NCT00568659 Completed Policlinico Hospital 2010-11-30
NCT00559130 Efficacy Study of CytoSorb Hemoperfusion Device on IL-6 Removal in ARDS/ALI Patients With Sepsis https://ClinicalTrials.gov/show/NCT00559130 Completed MedaSorb Technologies, Inc 2011-04-30
NCT00538928 Extrapulmonary Interventional Ventilatory Support in Severe Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT00538928 Completed University of Regensburg 2011-01-31
NCT00538161 Effect of Low Tidal Volume Ventilation in Improving Oxygenation and Thus Reducing Acute Lung Injury in the Cardiac Surgical Patient https://ClinicalTrials.gov/show/NCT00538161 Completed Beth Israel Deaconess Medical Center 2009-10-31
NCT00527813 Effect of Prone Positioning on Mortality in Patients With Severe and Persistent Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00527813 Completed Hospices Civils de Lyon 2011-08-31
NCT00498251 Prevention of Lung Edema After Thoracic Surgery https://ClinicalTrials.gov/show/NCT00498251 Completed University Hospital, Geneva NA
NCT00474656 The Oscillation for ARDS Treated Early (OSCILLATE) Trial Pilot Study https://ClinicalTrials.gov/show/NCT00474656 Completed Canadian Critical Care Trials Group 2008-07-31
NCT00465309 Protective Ventilation With Carbon Dioxide (CO2) -Removal Technique in Patients With Adult Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT00465309 Completed University of Turin, Italy NA
NCT00455767 Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients https://ClinicalTrials.gov/show/NCT00455767 Completed Debiopharm International SA 2007-09-30
NCT00431158 ARDSnet Protocol vs. Open Lung Approach in ARDS https://ClinicalTrials.gov/show/NCT00431158 Completed Massachusetts General Hospital 2012-09-30
NCT00416260 Combined High Frequency Oscillation and Tracheal Gas Insufflation for Severe Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00416260 Completed University of Athens 2007-09-30
NCT00399581 Comparison of Two Methods of High Frequency Oscillatory Ventilation in Individuals With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00399581 Completed Johns Hopkins University 2009-05-31
NCT00351533 A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) https://ClinicalTrials.gov/show/NCT00351533 Completed University of Washington 2009-01-31
NCT00314548 Inhaled Prostacyclin for Adult Respiratory Distress Syndrome (ARDS) and Pulmonary Hypertension https://ClinicalTrials.gov/show/NCT00314548 Completed Aga Khan University 2009-07-31
NCT00295269 Corticosteroids as Rescue Therapy for the Late Phase of Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00295269 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00290602 Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00290602 Completed National Cancer Center, Korea NA
NCT00284102 PEEP Test and Gas Exchange in ALI/ARDS Patients https://ClinicalTrials.gov/show/NCT00284102 Completed Policlinico Hospital 2008-04-30
NCT00281268 Fluids and Catheters Treatment Trial (FACTT) - ARDS Clinical Research Network https://ClinicalTrials.gov/show/NCT00281268 Completed National Heart, Lung, and Blood Institute (NHLBI) 2005-10-31
NCT00267241 Effects of Different Assisted Mechanical Ventilation in Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) Patients https://ClinicalTrials.gov/show/NCT00267241 Completed Policlinico Hospital 2014-11-30
NCT00240487 Nitric Oxide Administration for Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00240487 Completed Children’s Hospital of Philadelphia 2008-09-30
NCT00236262 Effect of Positive Expiratory Pressure on Right Ventricular Function in Patients With Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00236262 Completed Assistance Publique - Hôpitaux de Paris NA
NCT00219375 Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan https://ClinicalTrials.gov/show/NCT00219375 Completed Ono Pharmaceutical Co. Ltd 2007-07-31
NCT00217880 Significance of Biological Markers in Patients With Acute Lung Injury/Acute Respiratory Disease https://ClinicalTrials.gov/show/NCT00217880 Completed University of Michigan 2009-04-30
NCT00201409 A Randomized Trial of GM-CSF in Patients With ALI/ARDS https://ClinicalTrials.gov/show/NCT00201409 Completed University of Michigan 2009-05-31
NCT00188058 Comparison of 2 Strategies of Adjustment of Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00188058 Completed University Hospital, Angers 2006-01-31
NCT00182195 Lung Open Ventilation to Decrease Mortality in the Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00182195 Completed McMaster University NA
NCT00159939 Prone-Supine Study II: The Effect of Prone Positioning for Patients Affected by Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00159939 Completed Policlinico Hospital 2008-06-30
NCT00149513 Post-Hospital Case Management to Improve Clinical Outcomes in Individuals Requiring Mechanical Ventilation https://ClinicalTrials.gov/show/NCT00149513 Completed University of Washington 2009-02-28
NCT00143468 The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients https://ClinicalTrials.gov/show/NCT00143468 Completed Policlinico Hospital 2007-03-31
NCT00141726 Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant https://ClinicalTrials.gov/show/NCT00141726 Completed University of Michigan Rogel Cancer Center 2008-07-31
NCT00133614 Prone Positioning in Pediatric Acute Lung Injury https://ClinicalTrials.gov/show/NCT00133614 Completed National Institute of Nursing Research (NINR) NA
NCT00127491 Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury https://ClinicalTrials.gov/show/NCT00127491 Completed Beth Israel Deaconess Medical Center 2007-08-31
NCT00113685 Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury https://ClinicalTrials.gov/show/NCT00113685 Completed University of Washington NA
NCT00094406 Carbon Monoxide to Prevent Lung Inflammation https://ClinicalTrials.gov/show/NCT00094406 Completed National Institutes of Health Clinical Center (CC) 2010-03-11
NCT00036062 A Phase II Study to Determine the Efficacy and Safety of Sivelestat in Subjects With Acute Lung Injury https://ClinicalTrials.gov/show/NCT00036062 Completed Eli Lilly and Company NA
NCT00029328 Etanercept for Non-Infectious Lung Injury Following Bone Marrow Transplantation https://ClinicalTrials.gov/show/NCT00029328 Completed FDA Office of Orphan Products Development NA
NCT00000579 Acute Respiratory Distress Syndrome Clinical Network (ARDSNet) https://ClinicalTrials.gov/show/NCT00000579 Completed National Heart, Lung, and Blood Institute (NHLBI) NA
NCT00000574 Ibuprofen in Sepsis Study https://ClinicalTrials.gov/show/NCT00000574 Completed Vanderbilt University NA
NCT00000572 Extracorporeal Carbon Dioxide Removal for Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00000572 Completed Intermountain Health Care, Inc. 1991-04-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04460859 RecruitmEnt Assessed by eleCtRical Impedance Tomography https://ClinicalTrials.gov/show/NCT04460859 Recruiting St. Michael’s Hospital, Toronto 2021-12-31
NCT04457739 Assessment of Preload Responsiveness in ARDS Patients During Prone Position https://ClinicalTrials.gov/show/NCT04457739 Recruiting Bicetre Hospital 2020-12-31
NCT04383730 Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) https://ClinicalTrials.gov/show/NCT04383730 Recruiting University Hospital, Clermont-Ferrand 2020-11-30
NCT03379207 Innate Immune Response During Community Acquired Pneumonia https://ClinicalTrials.gov/show/NCT03379207 Recruiting University Hospital, Tours 2022-01-09
NCT03871166 Hemoglobin Concentration in Patients With an Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03871166 Recruiting Charite University, Berlin, Germany 2019-10-01
NCT03317431 the Effect of Dopamine on Mechanical Ventilation Induced Lung Injury https://ClinicalTrials.gov/show/NCT03317431 Completed Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2017-10-22
NCT03315702 Effect of Mechanical Ventilation on Plasma Concentration Level of R-spondin Proteins https://ClinicalTrials.gov/show/NCT03315702 Completed Xinhua Hospital, Shanghai Jiao Tong University School of Medicine 2017-10-15
NCT03236272 Establishment of a Biomarkers-based Early Warning System of Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03236272 Recruiting Third Military Medical University 2020-12-31
NCT03227289 Acute Respiratory Distress Syndrome(ARDS) in Neonates https://ClinicalTrials.gov/show/NCT03227289 Recruiting Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2018-07-30
NCT03225807 Implementation of Lung Protective Ventilation in Patients With Acute Respiratory Failure https://ClinicalTrials.gov/show/NCT03225807 Recruiting Intermountain Health Care, Inc. 2020-07-31
NCT03188770 Practice of Ventilation in Middle-Income Countries https://ClinicalTrials.gov/show/NCT03188770 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2018-11-29
NCT03179709 Provider Perceptions of Neuromuscular Blockade in ARDS https://ClinicalTrials.gov/show/NCT03179709 Completed University of Pittsburgh 2018-03-18
NCT03076983 Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time https://ClinicalTrials.gov/show/NCT03076983 Completed Drägerwerk AG & Co. KGaA 2018-04-12
NCT03038906 Effect of Randomization to Neuromuscular Blockade on Physical Functional Impairment and Recovery in ARDS https://ClinicalTrials.gov/show/NCT03038906 Recruiting University of Washington 2020-03-31
NCT03021824 Severe ARDS: Generating Evidence https://ClinicalTrials.gov/show/NCT03021824 Completed Montefiore Medical Center 2017-04-30
NCT02962505 Continuous Regional Analysis Device for Neonate Lung https://ClinicalTrials.gov/show/NCT02962505 Completed University of Schleswig-Holstein 2019-03-03
NCT02961166 Immunglobulin M Enriched Intra Venous Immunoglobulin (IVIG) Therapy in Adult Respiratory Distress Syndrom (ARDS) Patients https://ClinicalTrials.gov/show/NCT02961166 Completed University Hospital Tuebingen 2016-01-31
NCT02944279 Neutrophil Elastase and Elafin as Prognostic Biomarker for Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02944279 Completed Peking University Third Hospital 2014-08-31
NCT02889770 Dead Space Monitoring With Volumetric Capnography in ARDS Patients https://ClinicalTrials.gov/show/NCT02889770 Completed Hospital Italiano de Buenos Aires 2015-10-31
NCT02842788 Prevalence of Prone Positioning Use in ARDS Patients https://ClinicalTrials.gov/show/NCT02842788 Completed Hospices Civils de Lyon 2017-01-31
NCT02836444 Stratification of the Acute Respiratory Distress Syndrome - A Second Phase Study https://ClinicalTrials.gov/show/NCT02836444 Completed Dr. Negrin University Hospital 2017-05-01
NCT02732041 Asynchrony During Mechanical Ventilation in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02732041 Completed Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno 2018-11-22
NCT02711930 Effect of Prone Positioning on Intra-ocular Pressure in ARDS Patients https://ClinicalTrials.gov/show/NCT02711930 Completed Sanjay Gandhi Postgraduate Institute of Medical Sciences 2017-07-24
NCT02664090 Hemodynamic Assessment With Trans-esophageal Doppler (TED) During Prone Ventilation in ARDS Patients https://ClinicalTrials.gov/show/NCT02664090 Completed Sanjay Gandhi Postgraduate Institute of Medical Sciences 2017-01-18
NCT02638844 Assessment of Right Ventricular 2d-strain in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02638844 Completed Central Hospital, Nancy, France 2017-07-31
NCT02606240 Low-Flow CO2 Removal for Mild to Moderate ARDS With PRISMALUNG https://ClinicalTrials.gov/show/NCT02606240 Completed Groupe Hospitalier Pitie-Salpetriere 2017-06-30
NCT02545621 A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study https://ClinicalTrials.gov/show/NCT02545621 Completed University Hospital, Clermont-Ferrand 2016-09-30
NCT02490215 Epidemiology of Acute Respiratory Distress Syndrome in Chinese ICUs https://ClinicalTrials.gov/show/NCT02490215 Completed Peking Union Medical College Hospital 2015-08-31
NCT02475694 Acute Lung Injury After Cardiac Surgery: Pathogenesis https://ClinicalTrials.gov/show/NCT02475694 Completed Aalborg University Hospital 2009-03-31
NCT02415738 Changes in Cerebral Oxygenation During the Prone Position in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02415738 Completed Centre Hospitalier Bretagne Atlantique 2017-02-28
NCT02288949 Stratification of the Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02288949 Completed Dr. Negrin University Hospital 2015-07-31
NCT02265198 Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02265198 Completed Wake Forest University Health Sciences 2015-03-31
NCT02247700 Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography https://ClinicalTrials.gov/show/NCT02247700 Completed Boston Children’s Hospital 2018-11-04
NCT02232841 Electrical Impedance Imaging of Patients on Mechanical Ventilation https://ClinicalTrials.gov/show/NCT02232841 Completed Colorado State University 2016-08-31
NCT02214576 High Flow Nasal Canula Oxygen Helps Preoxygenate ARDS Patients https://ClinicalTrials.gov/show/NCT02214576 Completed Hôpital Louis Mourier 2015-08-31
NCT02184208 Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System. https://ClinicalTrials.gov/show/NCT02184208 Completed Boston Children’s Hospital 2016-12-30
NCT02178982 Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02178982 Completed Southeast University, China 2015-06-30
NCT02083393 Changes of Dendritic Cells in Acute Lung Injury https://ClinicalTrials.gov/show/NCT02083393 Completed Southeast University, China 2014-12-31
NCT02070536 Predictive Values of Plasma Soluble RAGE Levels and RAGE Polymorphisms for the Onset of Acute Respiratory Distress Syndrome in Critically Ill Patients https://ClinicalTrials.gov/show/NCT02070536 Completed University Hospital, Clermont-Ferrand 2016-03-31
NCT01270295 Soluble Forms and Ligands of RAGE in ALI/ARDS (SoLiRAGE). https://ClinicalTrials.gov/show/NCT01270295 Completed University Hospital, Clermont-Ferrand 2013-01-31
NCT02019095 Clinical and Biological Markers in Acute Respiratory Failure https://ClinicalTrials.gov/show/NCT02019095 Completed University of Athens 2014-12-31
NCT02010073 Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE https://ClinicalTrials.gov/show/NCT02010073 Completed European Society of Intensive Care Medicine 2014-08-31
NCT01926093 Low Dose Lung CT Scan for Quantitative Analysis in ARDS Patients https://ClinicalTrials.gov/show/NCT01926093 Completed Policlinico Hospital 2013-05-31
NCT01922557 Thoracic Fluid Content and Acute Lung Injury https://ClinicalTrials.gov/show/NCT01922557 Completed National Taiwan University Hospital 2011-01-31
NCT01878552 Energy Load in Patients With Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01878552 Completed Policlinico Hospital 2014-08-31
NCT01854424 Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS https://ClinicalTrials.gov/show/NCT01854424 Completed Assistance Publique - Hôpitaux de Paris 2016-07-31
NCT04262440 The Effect of Caloric Supplement in the Clinical Outcomes in Acute Lung Injury Patients https://ClinicalTrials.gov/show/NCT04262440 Recruiting Taichung Veterans General Hospital 2022-12-31
NCT01714583 The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol https://ClinicalTrials.gov/show/NCT01714583 Completed Yale University 2012-09-30
NCT01704066 Interobserver Variation in Applying a Radiographic Definition for Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01704066 Completed Society of Critical Care Medicine, China 2012-12-31
NCT01677130 Standardized Application of High Frequency Oscillatory Ventilation in the Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01677130 Completed Southeast University, China 2014-12-31
NCT01670747 Evaluation of the Lung Recruitment and End-expiratory Lung Collapse in Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01670747 Completed Policlinico Hospital 2015-03-31
NCT01666834 Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China https://ClinicalTrials.gov/show/NCT01666834 Completed Southeast University, China 2013-05-31
NCT01628523 Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study https://ClinicalTrials.gov/show/NCT01628523 Completed Washington University School of Medicine 2013-08-31
NCT01601223 Local Assessment of Ventilatory Management During General Anesthesia for Surgery https://ClinicalTrials.gov/show/NCT01601223 Completed European Society of Anaesthesiology 2013-05-31
NCT01486342 PET Imaging in Patients at Risk for Acute Lung Injury https://ClinicalTrials.gov/show/NCT01486342 Completed Washington University School of Medicine 2012-10-31
NCT01478217 PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment https://ClinicalTrials.gov/show/NCT01478217 Completed Sisters of Mercy University Hospital 2011-11-30
NCT01468142 Pulmonary Pathophysiology and Inflammatory Response in Patients Treated With Ecmo for Severe Respiratory Failure https://ClinicalTrials.gov/show/NCT01468142 Completed Karolinska University Hospital 2016-12-31
NCT01450527 Etiology and Outcomes of Tropical Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01450527 Completed All India Institute of Medical Sciences, New Delhi 2012-06-30
NCT01435889 Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01435889 Completed University Hospital, Lille 2014-10-31
NCT01322295 Human Bronchial Microdialysis in Open Aortic Aneurysm Repair https://ClinicalTrials.gov/show/NCT01322295 Completed Norwegian University of Science and Technology 2011-11-30
NCT01321398 Transpulmonary Pressure Gradients in High Frequency Oscillation https://ClinicalTrials.gov/show/NCT01321398 Completed University of British Columbia 2011-07-31
NCT04443491 Comparison of Esophageal and Central Venous Pressure for Estimating Transpulmonary Pressure Changes https://ClinicalTrials.gov/show/NCT04443491 Completed University of Siena 2019-03-31
NCT04435080 Physical Rehabilitation in ICU in ARDS Patients With COVID-19 https://ClinicalTrials.gov/show/NCT04435080 Completed Koç University 2020-06-11
NCT04411459 Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04411459 Recruiting Azienda Usl di Bologna 2020-06-30
NCT04408326 Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04408326 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2021-05-01
NCT04388813 Predictors of Severe COVID-19 Outcomes https://ClinicalTrials.gov/show/NCT04388813 Recruiting Verily Life Sciences LLC 2021-02-28
NCT04386720 Measurement of Airway Opening Pressure (AOP) in Patients With Acute Respiratory Distress Syndrom and With or Without Covid 19. https://ClinicalTrials.gov/show/NCT04386720 Recruiting University Hospital, Bordeaux 2021-05-25
NCT04385004 Clinical, Biological and Histological Pulmonary and Renal Damage Associated With the SARS-CoV-2 Syndrome in Patients Admitted in ICU https://ClinicalTrials.gov/show/NCT04385004 Recruiting University Hospital, Strasbourg, France 2020-07-31
NCT04405817 Outcome of Patients Treated With ECLS https://ClinicalTrials.gov/show/NCT04405817 Recruiting Nanjing Medical University 2025-12-31
NCT04376905 Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19) https://ClinicalTrials.gov/show/NCT04376905 Recruiting University Hospital, Montpellier 2020-09-01
NCT04370249 Construction of a Composite Clinical-echo Score Predictive of a Risk of Short-term Aggravation of Respiratory Impairment in Patients Suspected of Covid-19 https://ClinicalTrials.gov/show/NCT04370249 Recruiting Nantes University Hospital 2020-06-30
NCT02965079 Registry on the EXperience of Extracorporeal CO2 Removal in Intensive Care Units https://ClinicalTrials.gov/show/NCT02965079 Recruiting Rexecor 2020-01-31
NCT04337190 Impact of Angiotensin II Receptor Blockers Treatment in Patients With COVID 19 (COVID-ARA2) https://ClinicalTrials.gov/show/NCT04337190 Recruiting University Hospital, Angers 2020-10-06
NCT04319965 Complications Related to Transpulmonary Thermodilution https://ClinicalTrials.gov/show/NCT04319965 Recruiting Bicetre Hospital 2021-03-31
NCT04316884 Mechanisms for Organ Dysfunction in Covid-19 https://ClinicalTrials.gov/show/NCT04316884 Recruiting Uppsala University 2020-12-31
NCT04157946 The Role of Morphological Phenotype in ARDS https://ClinicalTrials.gov/show/NCT04157946 Completed Hospital El Cruce 2019-07-10
NCT04154007 Acute Kidney Injury in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04154007 Completed Zagazig University 2019-03-30
NCT04133558 Pulmonary Microbiota and ARDS Mortality https://ClinicalTrials.gov/show/NCT04133558 Recruiting University of Bordeaux 2020-11-01
NCT04113434 Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04113434 Recruiting Children’s Hospital of Philadelphia 2023-01-31
NCT04079426 Tetracycline to Limit the Innate Immune Response in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04079426 Recruiting University of Bonn 2021-01-31
NCT04078984 Driving Pressure as a Predictor of Mechanical Ventilation Weaning Time on Post-ARDS Patients in Pressure Support Ventilation. https://ClinicalTrials.gov/show/NCT04078984 Recruiting University Hospital, Bordeaux 2020-10-27
NCT04046380 A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies https://ClinicalTrials.gov/show/NCT04046380 Recruiting Changhua Christian Hospital 2021-06-30
NCT04009330 Clinical Evaluation of a Point of Care (POC) Assay to Identify Phenotypes in the Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04009330 Recruiting Queen’s University, Belfast 2021-06-30
NCT03969914 PEEP-induced Changed in RRI as Physiological Background of Ventilator-induced Kidney Injury https://ClinicalTrials.gov/show/NCT03969914 Recruiting Università degli Studi di Ferrara 2020-05-01
NCT03955887 Mitochondrial Dysfunction of Alveolar and Circulating Immune Cells During Acute Respiratory Distress Syndrome: Impact of Infectious Aggression and Alveolar Stretching as a Result of Mechanical Ventilation. https://ClinicalTrials.gov/show/NCT03955887 Recruiting Centre Hospitalier Universitaire Dijon 2021-01-31
NCT03946189 Comparison of the PaO2/FiO2 Ratio to Other Oxygenation Indexes for the Classification of Severity of Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03946189 Completed American University of Beirut Medical Center 2019-05-01
NCT03946150 PaO2/FiO2*PEEP (P/FP) Ratio and Mortality in Acute Respiratory Distress Syndrome. https://ClinicalTrials.gov/show/NCT03946150 Completed National University Health System, Singapore 2019-05-05
NCT03937947 Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study https://ClinicalTrials.gov/show/NCT03937947 Recruiting NHS Lothian 2020-10-31
NCT03920189 Echocardiographic Evaluation in ARDS Patients https://ClinicalTrials.gov/show/NCT03920189 Recruiting University of Milan 2020-09-01
NCT03828630 Lung Ultrasound to Detect Pulmonary Complications in Critically Ill Parturients https://ClinicalTrials.gov/show/NCT03828630 Completed Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) 2019-02-27
NCT03766204 The Role of Circulating CircRNAs and MicroRNAs in Acute Lung Injury https://ClinicalTrials.gov/show/NCT03766204 Recruiting Changhai Hospital 2023-12-31
NCT03763773 Prediction of Outcomes With a Miniaturized Transesophageal Echocardiography Probe in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03763773 Recruiting University Hospital, Lille 2021-05-31
NCT03709199 Long Term Follow up of Children Enrolled in the REDvent Study https://ClinicalTrials.gov/show/NCT03709199 Recruiting Children’s Hospital Los Angeles 2023-01-01
NCT03662230 Incidence and Severity of Acute Respiratory Distress Syndrome (ARDS) in the French Wounded Soldiers https://ClinicalTrials.gov/show/NCT03662230 Completed Direction Centrale du Service de Santé des Armées 2019-11-07
NCT03654352 The ASTERS Study: Assessing the Role of Sphingolipids in AcuTE Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03654352 Recruiting University of Kentucky 2020-12-31
NCT03641690 Serum and Bronchoalveolar Inflammatory Parameters in Patients With Severe Adult Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT03641690 Completed Centre Hospitalier Universitaire, Amiens 2017-12-01
NCT03539783 Identifying PARDS Endotypes https://ClinicalTrials.gov/show/NCT03539783 Recruiting Children’s Hospital Medical Center, Cincinnati 2024-03-31
NCT03504176 Pediatric Acute Respiratory Distress Syndrome Ventilation Bundle https://ClinicalTrials.gov/show/NCT03504176 Completed KK Women’s and Children’s Hospital 2020-05-12
NCT03424798 Measuring Heart and Lung Function in Critical Care https://ClinicalTrials.gov/show/NCT03424798 Recruiting University of Oxford 2019-09-30
NCT03415529 Impact of Arterial CO2 Tension on Management and Outcome in Patients With Acute Hypoxemic Respirator Failure and ARDS https://ClinicalTrials.gov/show/NCT03415529 Completed European Society of Intensive Care Medicine 2018-09-30
NCT01256333 Optimization of Arterial Oxygen Transport by Positive End-expiratory Pressure Variation in Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01256333 Completed Rennes University Hospital NA
NCT01187004 Extracardiac Complications After Cardiac Surgery https://ClinicalTrials.gov/show/NCT01187004 Completed University of Turin, Italy 2008-12-31
NCT01167621 Changes in Refractory Acute Respiratory Distress Syndrome (ARDS) Patients Under High Frequency Oscillation-ventilation https://ClinicalTrials.gov/show/NCT01167621 Completed Centre Hospitalier Universitaire de la Réunion 2012-09-30
NCT01161901 Impact of Inflammation Biomarkers on the Acute Respiratory Distress Syndrome (ARDS) Definition https://ClinicalTrials.gov/show/NCT01161901 Completed University Hospital, Clermont-Ferrand 2011-11-30
NCT01159392 Alveolar Recruitment in Brain Injury https://ClinicalTrials.gov/show/NCT01159392 Completed Hospital Clinic of Barcelona NA
NCT01142544 Incidence of Acute Lung Injury in Children https://ClinicalTrials.gov/show/NCT01142544 Completed Dr. Negrin University Hospital 2011-02-28
NCT01105663 Pharmacologic Impact on Sedation Assessments https://ClinicalTrials.gov/show/NCT01105663 Completed Children’s Hospital of Philadelphia 2013-12-31
NCT01102322 Factors Associated With the Use of Lung Protective Ventilation Strategy (LPV) in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients in Intensive Care Unit (ICU) https://ClinicalTrials.gov/show/NCT01102322 Completed National Taiwan University Hospital 2011-01-31
NCT01089400 Immuno-virological Characterization of Severe H1N1v Influenza Infection in Bronchoalveolar Lavage https://ClinicalTrials.gov/show/NCT01089400 Completed Institut National de la Santé Et de la Recherche Médicale, France NA
NCT01078831 Intrabronchial Airway Pressures in Intubated Patients During Bronchoscopy https://ClinicalTrials.gov/show/NCT01078831 Completed Oslo University Hospital 2010-04-30
NCT00980915 Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury https://ClinicalTrials.gov/show/NCT00980915 Active, not recruiting Mayo Clinic 2020-12-31
NCT00889772 Lung Injury Prediction Study https://ClinicalTrials.gov/show/NCT00889772 Completed Mayo Clinic 2010-02-28
NCT04378582 Characteristics and Outcomes of Patients With COVID-19 Admitted to the ICU https://ClinicalTrials.gov/show/NCT04378582 Recruiting University of Sao Paulo General Hospital 2020-08-30
NCT03351920 Ventilation’s Parameters Applied in Emergency Medicine. A Prospective Observational Study https://ClinicalTrials.gov/show/NCT03351920 Completed Poitiers University Hospital 2019-07-22
NCT00826072 Inflammatory Genetic Polymorphism and Acute Lung Injury After Cardiac Surgery https://ClinicalTrials.gov/show/NCT00826072 Completed Changhai Hospital 2008-11-30
NCT00825357 Biological Markers to Identify Early Sepsis and Acute Lung Injury https://ClinicalTrials.gov/show/NCT00825357 Completed Chimei Medical Center 2011-08-31
NCT03753412 Recovery From ICUAW Following Severe Respiratory and Cardiac Failure https://ClinicalTrials.gov/show/NCT03753412 Recruiting Barts & The London NHS Trust 2020-08-01
NCT04449081 Knowledge, Attitude and Practice of Dental Students About COVID-19 https://ClinicalTrials.gov/show/NCT04449081 Completed Melaka Manipal Medical College 2020-06-10
NCT00811629 Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients https://ClinicalTrials.gov/show/NCT00811629 Completed University Hospital, Clermont-Ferrand 2009-07-31
NCT04383678 Outcome of COVID-19 Patients After Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT04383678 Recruiting Helsinki University Central Hospital 2020-12-31
NCT04350710 Description of Respiratory Mechanics in Patients With SARS-CoV-2 Associated ARDS https://ClinicalTrials.gov/show/NCT04350710 Recruiting University Hospital, Angers 2020-04-20
NCT02739438 The Study of ELEctronic Cigarette Toxicity in a Human Model in Vivo Model of Inflammation and Vascular Dysfunction https://ClinicalTrials.gov/show/NCT02739438 Recruiting Queen’s University, Belfast 2019-12-31
NCT02549222 A Open Label, Post Marketing Surveillance Study Following Transfusion of INTERCEPT Platelet Components https://ClinicalTrials.gov/show/NCT02549222 Enrolling by invitation Cerus Corporation 2020-09-30
NCT02457741 Validation of a Simple Approach to Estimate Alveolar Recruitability in ARDS Patients https://ClinicalTrials.gov/show/NCT02457741 Completed St. Michael’s Hospital, Toronto 2017-12-31
NCT02201446 The Role of Circulating Soluble CD74 in Acute Lung Injury https://ClinicalTrials.gov/show/NCT02201446 Completed Changhai Hospital 2014-11-30
NCT03715647 Correlation of Survival in Puerperae by Electrical Impedance Tomography https://ClinicalTrials.gov/show/NCT03715647 Completed Amazon University 2017-12-31
NCT04411368 Impact of Respiratory Virus in Critically Ill Patients With Acute Respiratory Failure https://ClinicalTrials.gov/show/NCT04411368 Recruiting Seoul St. Mary’s Hospital 2022-12-31
NCT00736892 Incidence of Acute Lung Injury: The Alien Study https://ClinicalTrials.gov/show/NCT00736892 Completed Villar, Jesus, M.D. 2010-03-31
NCT00719446 Evaluating Health Outcomes and QOL After ALI Among Participants of the ALTA, OMEGA, EDEN, and SAILS ARDS Network Trials https://ClinicalTrials.gov/show/NCT00719446 Completed Johns Hopkins University 2014-10-31
NCT00682942 How to Predict Lung Recruitment at the Bedside in Patients Affected by Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) https://ClinicalTrials.gov/show/NCT00682942 Completed Policlinico Hospital 2011-06-30
NCT00673517 The Effect of High Frequency Oscillation on Biological Markers of Lung Injury https://ClinicalTrials.gov/show/NCT00673517 Completed St. Michael’s Hospital, Toronto 2008-11-30
NCT00659152 Morphofunctional Lung Analysis by Positron Emission Tomography https://ClinicalTrials.gov/show/NCT00659152 Completed Policlinico Hospital 2013-12-31
NCT00557414 Serial Changes of Soluble Triggering Receptor Expressed on Myeloid Cells-1 (sTREM-1) Levels in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00557414 Completed National Taiwan University Hospital NA
NCT00548795 Viral-Related Neutrophil Response and Condition Severity in People With ARDS https://ClinicalTrials.gov/show/NCT00548795 Completed National Jewish Health 2011-01-31
NCT00521625 Epidemiologic Multicenter Study on Mechanical Ventilation Management in Children With Acute Lung Injury https://ClinicalTrials.gov/show/NCT00521625 Completed St. Justine’s Hospital NA
NCT00458926 Enhancing Utilization of Non-Invasive Positive Pressure Ventilation in Critical Care https://ClinicalTrials.gov/show/NCT00458926 Active, not recruiting Tufts Medical Center 2009-12-31
NCT00446706 Estimation of Intrinsic Positive End-Expiratory Pressure (PEEP) in Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT00446706 Completed Texas Tech University Health Sciences Center, El Paso 2007-04-30
NCT00440882 Changes of Transforming Growth Factor b1 and Procollagen III in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00440882 Completed Assistance Publique Hopitaux De Marseille NA
NCT00435110 Effects of PEEP and FIO2 in ALI and ARDS https://ClinicalTrials.gov/show/NCT00435110 Completed Instituto Canario de Investigacion Biomedica NA
NCT00819871 Nuclear Factor Kappa-B (NFKB1) Polymorphism and Organ Injury After Cardiac Surgery https://ClinicalTrials.gov/show/NCT00819871 Completed Changhai Hospital 2008-10-31
NCT00300248 Long-Term Results in Mechanically Ventilated Individuals With Acute Lung Injury/Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00300248 Completed Johns Hopkins University 2012-10-31
NCT00258518 Respiratory Mechanics and Pleural Effusion https://ClinicalTrials.gov/show/NCT00258518 Completed Policlinico Hospital 2011-06-30
NCT00234767 Study of the Economics of Pulmonary Artery Catheter Use in Patients With Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT00234767 Completed University of Pittsburgh 2007-08-31
NCT00157144 Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005 https://ClinicalTrials.gov/show/NCT00157144 Completed Bayside Health 2006-08-31
NCT00155779 ACE Gene Polymorphism and ARDS Outcome https://ClinicalTrials.gov/show/NCT00155779 Completed National Taiwan University Hospital NA
NCT00142376 Short Term Outcomes of Children With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT00142376 Completed Nationwide Children’s Hospital NA
NCT00006496 Molecular Epidemiology of ARDS https://ClinicalTrials.gov/show/NCT00006496 Recruiting Massachusetts General Hospital 2022-08-31
NCT00005318 ARDS - Clinical Epidemiology and the Role of the Inflammatory Response - SCOR in Acute Lung Injury https://ClinicalTrials.gov/show/NCT00005318 Completed University of Minnesota NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT04457505 One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 https://ClinicalTrials.gov/show/NCT04457505 Recruiting Consorcio Centro de Investigación Biomédica en Red, M.P. 2021-05-31
NCT03311165 Epidemiological Study of Neonatal Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT03311165 Completed Daping Hospital and the Research Institute of Surgery of the Third Military Medical University 2019-06-30
NCT02799940 Abnormalities in Lung Computed Tomography and Physiological Alterations in Patients With Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT02799940 Completed Hospital Regional Rio Gallegos 2019-05-19
NCT02613377 Transfusion-related Acute Lung Injury: a Prospective Cohort Study in Critically Ill Children https://ClinicalTrials.gov/show/NCT02613377 Active, not recruiting St. Justine’s Hospital 2020-01-31
NCT02492204 The Role of IL33/ST2 Axis in ARDS Patients https://ClinicalTrials.gov/show/NCT02492204 Completed Hospital Universitari Vall d’Hebron Research Institute 2015-07-31
NCT02320539 MicroRNA Diagnostics in Subarachnoid Hemorrhage 2 https://ClinicalTrials.gov/show/NCT02320539 Completed Rigshospitalet, Denmark 2015-05-31
NCT04387669 Maneuver for Evaluating the Potential Recruitability of the Pulmonary Parenchyme in Patients With ARDS https://ClinicalTrials.gov/show/NCT04387669 Recruiting University Hospital, Caen 2021-10-20
NCT04158479 China Extracorporeal Life Support Registry https://ClinicalTrials.gov/show/NCT04158479 Recruiting Beijing Anzhen Hospital 2025-12-31
NCT04068038 Pediatric Acute Respiratory Distress Syndrome Asia Study https://ClinicalTrials.gov/show/NCT04068038 Recruiting KK Women’s and Children’s Hospital 2022-08-01
NCT04031794 ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory Failure https://ClinicalTrials.gov/show/NCT04031794 Recruiting Mahidol University 2025-07-30
NCT03969407 Determination of the Best Positive End-expiratory Pressure (PEEP) https://ClinicalTrials.gov/show/NCT03969407 Completed Centre Chirurgical Marie Lannelongue 2019-06-20
NCT03513809 Inflammation and Distribution of Pulmonary Ventilation Before and After Tracheal Intubation in ARDS Patients https://ClinicalTrials.gov/show/NCT03513809 Recruiting Pontificia Universidad Catolica de Chile 2021-06-08
NCT03255109 WorldwidE AssessmeNt of Separation of pAtients From Ventilatory assistancE https://ClinicalTrials.gov/show/NCT03255109 Completed European Society of Intensive Care Medicine 2018-05-31
NCT04209270 Breathing Pattern, WOB and Gas Exchange in Patients With Acute Respiratory Distress Syndrome During the Spontaneous Breathing Trial https://ClinicalTrials.gov/show/NCT04209270 Recruiting Sanatorio de la Trinidad Mitre 2022-12-01